Proline Rich 5 (Renal) (PRR5) (C-Term) Peptide
PRR5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PRR5 products
- PRR5 (Proline Rich 5 (Renal) (PRR5))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PRR5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PRR5 (Proline Rich 5 (Renal) (PRR5))
- Synonyms
- AU043908 Peptide, Arhgap8 Peptide, C030017C09Rik Peptide, C78947 Peptide, Protor-1 Peptide, Protor1 Peptide, FLJ20185k Peptide, PP610 Peptide, PROTOR-1 Peptide, PROTOR1 Peptide, pp610 Peptide, protor1 Peptide, protor2 Peptide, proline rich 5 (renal) Peptide, proline rich 5 Peptide, proline rich 5 L homeolog Peptide, Prr5 Peptide, PRR5 Peptide, prr5.L Peptide
- Background
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This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Alias Symbols: PP610, PROTOR1, PROTOR-1, FLJ20185k
Protein Size: 293 - Molecular Weight
- 41 kDa
- Gene ID
- 55615
- NCBI Accession
- NM_001017528, NP_056181
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