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Proteasome Subunit Alpha Type 3 (PSMA3) (Middle Region) Peptide

PSMA3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982341
  • Target See all PSMA3 products
    PSMA3 (Proteasome Subunit Alpha Type 3 (PSMA3))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PSMA3 antibody (Catalog #: ARP57743_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PSMA3 (Proteasome Subunit Alpha Type 3 (PSMA3))
    Synonyms
    HC8 Peptide, PSC3 Peptide, Psma3l Peptide, psma3 Peptide, im:6909944 Peptide, zgc:114044 Peptide, Lmpc8 Peptide, proteasome subunit alpha 3 Peptide, proteasome subunit alpha 3 L homeolog Peptide, proteasome (prosome, macropain) subunit, alpha type 3 Peptide, PSMA3 Peptide, Psma3 Peptide, psma3.L Peptide, psma3 Peptide
    Background
    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

    Alias Symbols: HC8, MGC12306, MGC32631, PSC3

    Protein Interaction Partner: ATN1,AURKB,BAT2,CDKN1A,CRYAB,CSNK2A1,EGR1,GFI1B,HHEX,PLK1,PRNP,PSMA1,PSMA2,PSMA4,PSMA6,PSMA7,PSMB5,RERE,SNRPB,SNRPF,STUB1,STX11,XRN2,BAT2,CDKN1A,CRYAB,EGR1,GIYD2,PLK1,PSMA1,PSMA6,PSMD13,PSMD14,SNRPB,SNRPF,STX11,TRIB3,XRN2

    Protein Size: 248
    Molecular Weight
    28 kDa
    Gene ID
    5684
    NCBI Accession
    NM_152132, NP_687033
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