Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2) (Middle Region) Peptide
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- Target See all PSMB2 products
- PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMB2 antibody (Catalog #: ARP56462_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))
- Synonyms
- HC7-I Peptide, 19.m02268 Peptide, DDBDRAFT_0190287 Peptide, DDBDRAFT_0232958 Peptide, DDB_0190287 Peptide, DDB_0232958 Peptide, Psmb2 Peptide, ACYPI004276 Peptide, AU045357 Peptide, AW108089 Peptide, C7-I Peptide, D4Wsu33e Peptide, zgc:92282 Peptide, proteasome subunit beta 2 Peptide, proteasome subunit beta type 2 Peptide, proteasome beta 2 subunit Peptide, putative proteasome beta 2 subunit Peptide, 20S proteasome subunit beta-2 Peptide, proteasome (prosome, macropain) subunit, beta type 2 Peptide, proteasome subunit beta 2 L homeolog Peptide, PSMB2 Peptide, CNC04990 Peptide, Tc00.1047053510287.30 Peptide, Tc00.1047053503891.100 Peptide, Tc00.1047053508461.430 Peptide, LBRM_34_3820 Peptide, LBRM_35_0400 Peptide, BBOV_I004450 Peptide, LMJF_36_0320 Peptide, psmB2 Peptide, Psmb2 Peptide, psmb2 Peptide, psmb2.L Peptide
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC7-I, MGC104215, MGC126885
Protein Interaction Partner: tat,PLK1,PSMA1,PSMB3,GIYD2
Protein Size: 201 - Molecular Weight
- 23 kDa
- Gene ID
- 5690
- NCBI Accession
- NM_002794, NP_002785
- UniProt
- P49721
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