Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) (Middle Region) Peptide
PSMB5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PSMB5 products
- PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMB5 antibody (Catalog #: ARP56467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))
- Synonyms
- LMPX Peptide, MB1 Peptide, X Peptide, etID309919.2 Peptide, fb59c07 Peptide, si:zc14a17.13 Peptide, wu:fb59c07 Peptide, x Peptide, zgc:86820 Peptide, proteasome subunit beta 5 Peptide, proteasome (prosome, macropain) subunit, beta type 5 Peptide, proteasome subunit beta 5 L homeolog Peptide, proteasome (prosome, macropain) subunit, beta type, 5 Peptide, PSMB5 Peptide, psmb5 Peptide, Psmb5 Peptide, psmb5.L Peptide
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB5 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LMPX, MB1, MGC104214, X
Protein Interaction Partner: tat,ABCB5,LSM1,PIK3R1,PLK1,POMP,PSMA1,PSMA2,PSMA3,PSMB1,PSMB3,PSMB7,TAP1,TAP2,TRAF6,GIYD2,LSM1,PLK1,PSMD6,TRAF6,UCHL5,USP14
Protein Size: 263 - Molecular Weight
- 28 kDa
- Gene ID
- 5693
- NCBI Accession
- NM_002797, NP_002788
- UniProt
- P28074
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