Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptide

Details for Product No. ABIN982476, Supplier: Log in to see
Protein Name
  • CAGER-1
  • Pur-alpha
  • ssCRE-BP
  • PUR-ALPHA
  • PUR1
  • PURALPHA
  • zgc:103411
  • pur-alpha
  • pur1
  • puralpha
  • purine-rich element binding protein A
  • purine rich element binding protein A
  • pura
  • Pura
  • PURA
Protein Region
N-Term
Origin
Human
2
1
1
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-PURA antibody (Purine-Rich Element Binding Protein A) (N-Term) (ABIN2777801)
Sequence MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA
Characteristics This is a synthetic peptide designed for use in combination with anti- PURA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Alias Symbols: PUR1, MRD31, PURALPHA, PUR-ALPHA

Protein Size: 322
Molecular Weight 35 kDa
Gene ID 5813
NCBI Accession NM_005859, NP_005850
UniProt Q00577
Research Area DNA/RNA, Chromatin Binding Proteins, Transcription Factors, Chromatin and Nuclear Signaling
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.