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RAD23 Homolog B (RAD23B) (Middle Region) Peptide

RAD23B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982606
  • Target See all RAD23B products
    RAD23B (RAD23 Homolog B (RAD23B))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    QSSAVAAAAA TTTATTTTTS SGGHPLEFLR NQPQFQQMRQ IIQQNPSLLP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RAD23B Antibody(ARP56505_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RAD23B (RAD23 Homolog B (RAD23B))
    Synonyms
    HHR23B Peptide, HR23B Peptide, P58 Peptide, 0610007D13Rik Peptide, AV001138 Peptide, mHR23B Peptide, p58 Peptide, MGC107846 Peptide, zgc:65951 Peptide, RAD23 homolog B, nucleotide excision repair protein Peptide, UV excision repair protein RAD23 homolog B Peptide, RAD23 homolog B, nucleotide excision repair protein S homeolog Peptide, RAD23B Peptide, Rad23b Peptide, rd23b Peptide, rad23b Peptide, rad23b.S Peptide
    Background
    The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

    Alias Symbols: HHR23B, HR23B, P58

    Protein Interaction Partner: ATXN3,ATXN3,MPG,NGLY1,PSMD4,PSMD4,TDG,UBB,XPC,ZFAND5,ATXN3,OTUD1,PAX3,PSMD4,UCHL5,XPC

    Protein Size: 409
    Molecular Weight
    43 kDa
    Gene ID
    5887
    NCBI Accession
    NM_002874, NP_002865
    UniProt
    P54727
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