Retinoic Acid Receptor, alpha (RARA) (N-Term) Peptide
RARA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Retinoic Acid Receptor alpha (RARA) products
- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RARA antibody (Catalog #: ARP40314_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Retinoic Acid Receptor, alpha (RARA) peptide
RARA Reactivity: Human, Mouse, Cow, Dog, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
- Synonyms
- NR1B1 Peptide, RAR Peptide, Nr1b1 Peptide, RARalpha1 Peptide, rar-alpha Peptide, etID309833.12 Peptide, rara Peptide, rara2a Peptide, zRAR Peptide, zRAR-alpha Peptide, zgc:109797 Peptide, nr1b1 Peptide, RAR-ALPHA1 Peptide, HS-RARa Peptide, fj66e06 Peptide, rara2b Peptide, wu:fj66e06 Peptide, retinoic acid receptor alpha Peptide, retinoic acid receptor, alpha Peptide, retinoic acid receptor, alpha a Peptide, retinoic acid receptor alpha L homeolog Peptide, retinoic acid receptor, alpha b Peptide, RARA Peptide, Rara Peptide, LOC100136372 Peptide, raraa Peptide, rara.L Peptide, rara Peptide, rarab Peptide
- Background
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Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
Alias Symbols: NR1B1, RAR
Protein Interaction Partner: NCOR1,NCOR2,ANP32A,BTG1,CDK7,KDM5A,MED6,NCOA1,NCOA2,NCOA3,PARP1,PRMT2,TNFRSF10B,BAG1,BTG1,CCND3,CDK7,CNOT1,COPS2,ESR1,FOXO1,GADD45G,GATA2,IRX4,ITGB1BP2,KAT2B,KDM5A,KLF5,MECR,MED1,MED6,NCOA1,NCOA3,NCOA6,NCOR1,NCOR2,NKX2-1,NPAS2,NR0B2,NR1H2,NR1H3,NR2E3,NRBF2,NRIP1,NRIP2,NSD1,PARP1,PML,PNRC2,POU2F1,PRDX6,PRKCA,RXRA,RXRB,RXRG,SNW1,SP1,SPEN,STAT5B,TADA3,TRIM24,TRIP4,UBE3A,ZBTB16,ARNTL,BAG1,CCND3,CLOCK,GADD45A,GADD45G,Gadd45b,HDAC3,HDAC4,IRX4,JUB,KAT2B,KDM5A,LIMD1,MECR,NCOA2,NCOA6,NCOR1,NCOR2,NKX2-1,NPAS2,NR0B2,NR2E3,NR4A2,NRBF2,NRIP1,Nr0b2,Nsd1,PML,POU2F1,RARA,RXRA,RXRB,RXRG,SKI,SP1,SRC,TADA3,TDG,TRIM24,TRIP4,WTIP,ZBTB16
Protein Size: 457 - Molecular Weight
- 51 kDa
- Gene ID
- 5914
- NCBI Accession
- NM_001024809, NP_001019980
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