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RNA Binding Motif Protein 5 (RBM5) (N-Term) Peptide

RBM5 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982753
  • Target See all RBM5 products
    RBM5 (RNA Binding Motif Protein 5 (RBM5))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RBM5 antibody (Catalog #: ARP38684_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RBM5 (RNA Binding Motif Protein 5 (RBM5))
    Synonyms
    wu:fc25a08 Peptide, wu:fe06f12 Peptide, g15 Peptide, h37 Peptide, luca15 Peptide, rbm5 Peptide, rmb5 Peptide, RBM5 Peptide, G15 Peptide, LUCA15 Peptide, RMB5 Peptide, D030069N10Rik Peptide, RNA binding motif protein 5 Peptide, RNA binding motif protein 5 S homeolog Peptide, RNA binding motif protein 5 L homeolog Peptide, rbm5 Peptide, rbm5.S Peptide, RBM5 Peptide, rbm5.L Peptide, Rbm5 Peptide
    Background
    RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

    Alias Symbols: FLJ39876, G15, H37, LUCA15, RMB5

    Protein Interaction Partner: C1orf103,C1orf103

    Protein Size: 815
    Molecular Weight
    92 kDa
    Gene ID
    10181
    NCBI Accession
    NM_005778, NP_005769
    UniProt
    P52756
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