RFT1 Homolog (RFT1) Peptide
RFT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RFT1 products
- RFT1 (RFT1 Homolog (RFT1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RFT1 antibody (Catalog #: ARP50203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RFT1 (RFT1 Homolog (RFT1))
- Synonyms
- GB14370 Peptide, CDG1N Peptide, D930025H04 Peptide, RGD1562654 Peptide, protein RFT1 homolog Peptide, RFT1 homolog Peptide, LOC412489 Peptide, LOC100453537 Peptide, RFT1 Peptide, rft1 Peptide, LOC100633251 Peptide, LOC100651701 Peptide, Rft1 Peptide
- Background
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N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a??Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
Alias Symbols: CDG1N
Protein Size: 541 - Molecular Weight
- 60 kDa
- Gene ID
- 91869
- NCBI Accession
- NM_052859, NP_443091
- UniProt
- Q96AA3
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