Ras Homolog Gene Family, Member C (RHOC) (N-Term) Peptide
RHOC
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all RHOC products
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RHOC antibody (Catalog #: ARP55742_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Synonyms
- ARHC Peptide, LOC100221682 Peptide, ARH9 Peptide, H9 Peptide, RHOH9 Peptide, AI324259 Peptide, Arh9 Peptide, Arhc Peptide, CRHOC Peptide, ras homolog family member C L homeolog Peptide, ras homolog family member C Peptide, rhoc.L Peptide, RHOC Peptide, rhoc Peptide, Rhoc Peptide
- Background
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RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
Protein Interaction Partner: ARHGAP1,CIT,DIAPH1,ROCK1,RTKN,ARHGAP1,ARHGDIA,CIT,VHL
Protein Size: 193 - Molecular Weight
- 22 kDa
- Gene ID
- 389
- NCBI Accession
- NM_175744, NP_786886
- UniProt
- P08134
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