Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (Middle Region) Peptide
SDHB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SDHB products
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SDHB antibody (Catalog #: ARP47981_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) peptide
SDHB Reactivity: Human Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
- Synonyms
- succinate dehydrogenase 2-3 Peptide, CG3283 Peptide, Dmel\\CG3283 Peptide, Ip Peptide, SDH Peptide, SDH-IP Peptide, SDH-Ip Peptide, SDHb Peptide, sdhB Peptide, CWS2 Peptide, IP Peptide, PGL4 Peptide, SDH1 Peptide, SDH2 Peptide, SDHIP Peptide, 0710008N11Rik Peptide, fj46d06 Peptide, wu:fj46d06 Peptide, succinate dehydrogenase complex iron sulfur subunit B Peptide, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 Peptide, Succinate dehydrogenase, subunit B (iron-sulfur) Peptide, succinate dehydrogenase complex subunit B, iron sulfur (Ip) Peptide, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) Peptide, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog Peptide, SDHB Peptide, SDH2-3 Peptide, SdhB Peptide, sdhb Peptide, Sdhb Peptide, sdhb.S Peptide
- Background
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Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IP, PGL4, SDH, SDH1, SDHIP, SDH2
Protein Interaction Partner: ABCA1
Protein Size: 280 - Molecular Weight
- 31 kDa
- Gene ID
- 6390
- NCBI Accession
- NM_003000, NP_002991
- UniProt
- P21912
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