Stratifin (SFN) (Middle Region) Peptide
SFN
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all 14-3-3 sigma/SFN (SFN) products
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SFN antibody (Catalog #: ARP54792_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Synonyms
- YWHAS Peptide, Er Peptide, Mme1 Peptide, Ywhas Peptide, stratifin Peptide, SFN Peptide, Sfn Peptide
- Background
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SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Alias Symbols: YWHAS
Protein Interaction Partner: TP53,TP53,ABL1,BAD,BAX,BCR,CCAR1,CDC25B,CDK1,CHST1,EEF1A1,EGFR,EIF2S1,EIF4B,FAM189A2,GPRIN2,HDAC5,HNRNPD,ING1,KCNK15,KCNK3,KCNK9,KIAA0408,MAP3K5,MARK3,MDM4,MST1R,NR3C1,PLEKHF2,PLK4,TBL3,TRIM25,TSC2,WDYHV1,YWHAG,ZFP36,ABLIM1,ANKS1A,APC,APLP2,ARAF,ARHGAP11A,ARHGAP21,ARHGAP32,ARHGEF16,ARHGEF17,ARHGEF5,BAD,BCAR1,BRAF,CDK1,CGN,CHEK1,CHST1,CSNK2A1,CYTH2,DCAF7,DTX2,DYRK1A,ERRFI1,FAM189A2,GAN,GPRIN2,GRB7,HDAC4,HDAC7,HNRNPU,IRS1,IRS2,ISCU,ITCH,JUB,KIAA0408,KIF23,KIF5B,KLC1,KLC2,KLHDC2,LAD1,LMO7,LSR,MAGI1,MAP3K2,MAPKAP1,MARK1,MARK2,MARK3,MDM2,MPRIP,MYCBP2,NEDD4L,NR3C1,OSBPL3,PAK4,PARD3,PARD3B,PI4KB,PIK3C2B,PKP2,PKP3,PLEKHF2,PLK4,PPFIBP1,PPFIBP2,PPP1R3D,PTOV1,PTPN2,PTPN3,RACGAP1,RAE1,RAF1,RALGPS2,RHPN2,RND3,SASH1,SAV1,SH2D3A,SH3BP4,SHCBP1,SHROOM3,SIPA1L1,SIPA1L3,SORBS2,SPIRE1,SRRM2,SRSF10,ST5,SYNJ2,TBL3,TJP2,TNK1,TNS4,TP53,TRIM25,TRIM32,UBC,USP8,WDYHV1,WEE1,YWHAG,ZAK,ZNF638
Protein Size: 248 - Molecular Weight
- 28 kDa
- Gene ID
- 2810
- NCBI Accession
- NM_006142, NP_006133
- UniProt
- P31947
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