Short Stature Homeobox 2 (SHOX2) (N-Term) Peptide
SHOX2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SHOX2 products
- SHOX2 (Short Stature Homeobox 2 (SHOX2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SHOX2 antibody (Catalog #: ARP33285_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SHOX2 (Short Stature Homeobox 2 (SHOX2))
- Synonyms
- SHOX2 Peptide, og12 Peptide, shot Peptide, og12x Peptide, ogi2x Peptide, OG12 Peptide, OG12X Peptide, SHOT Peptide, 6330543G17Rik Peptide, Og12x Peptide, Prx3 Peptide, zgc:65884 Peptide, zgc:77344 Peptide, short stature homeobox 2 Peptide, SHOX2 Peptide, shox2 Peptide, Shox2 Peptide
- Background
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SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
Alias Symbols: OG12, OG12X, OGI2X, SHOT
Protein Size: 331 - Molecular Weight
- 35 kDa
- Gene ID
- 6474
- NCBI Accession
- NM_006884, NP_006875
- UniProt
- O60902
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