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Nucleotide Exchange Factor SIL1 (SIL1) Peptide

SIL1 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN983747
  • Target See all SIL1 products
    SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SIL1 antibody (Catalog #: ARP44848_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))
    Synonyms
    1810057E01Rik Peptide, AI042831 Peptide, wz Peptide, BAP Peptide, MSS Peptide, ULG5 Peptide, endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) Peptide, SIL1 nucleotide exchange factor L homeolog Peptide, SIL1 nucleotide exchange factor Peptide, Sil1 Peptide, sil1.L Peptide, SIL1 Peptide
    Background
    SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

    Alias Symbols: BAP, MSS, ULG5

    Protein Interaction Partner: HSPA5,SMAD9,HSPA5

    Protein Size: 461
    Molecular Weight
    49 kDa
    Gene ID
    64374
    NCBI Accession
    NM_022464, NP_071909
    UniProt
    Q9H173
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