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SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin) Peptide

Reactivity: Human Host: Synthetic BP, ChIP, WB
Catalog No. ABIN984112
  • Target
    SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin)
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SMARCA5 antibody (Catalog #: ARP30031_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin)
    Background
    SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ISWI, SNF2H, WCRF135, hISWI, hSNF2H

    Protein Interaction Partner: ALB,BAZ1A,DNMT3B,H3F3A,HDAC2,HNF1A,BAZ1A,BAZ1B,BAZ2A,CHRAC1,CREB1,DNMT3B,H3F3B,HDAC2,HIST2H4A,MAF,RAD21,RSF1,SATB1,BAZ1A,BAZ1B,BAZ2A,Bmi1,CDT1,CHD3,CHRAC1,Cbx2,DNMT3B,HDAC2,POLE3,RAD21,RBBP4,SATB1,SMC1A,SMC3

    Protein Size: 1052
    Molecular Weight
    122 kDa
    Gene ID
    8467
    NCBI Accession
    NM_003601, NP_003592
    UniProt
    O60264
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