Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5) (N-Term) Peptide
SMG5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SMG5 products
- SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMG5 antibody (Catalog #: ARP55229_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
- Synonyms
- BC024683 Peptide, mKIAA1089 Peptide, EST1B Peptide, LPTS-RP1 Peptide, LPTSRP1 Peptide, SMG-5 Peptide, SMG5, nonsense mediated mRNA decay factor Peptide, Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) Peptide, SMG5 nonsense mediated mRNA decay factor Peptide, SMG5 Peptide, Smg5 Peptide
- Background
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SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].
Alias Symbols: EST1B, FLJ34864, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5
Protein Interaction Partner: SMG7,SMG1,SMG6,SMG7,TERT,UPF1,TERT
Protein Size: 1016 - Molecular Weight
- 114 kDa
- Gene ID
- 23381
- NCBI Accession
- NM_015327, NP_056142
- UniProt
- Q9UPR3
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