Sepiapterin Reductase (SPR) (C-Term) Peptide
SPR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SPR products
- SPR (Sepiapterin Reductase (SPR))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPR Antibody(ARP59628_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SPR (Sepiapterin Reductase (SPR))
- Synonyms
- SDR38C1 Peptide, AA409688 Peptide, ENSMUSG00000071345 Peptide, Gm10328 Peptide, CG12117 Peptide, Dmel\\CG12117 Peptide, SR Peptide, sptr Peptide, xspr Peptide, DDBDRAFT_0188686 Peptide, DDBDRAFT_0191275 Peptide, DDB_0188686 Peptide, DDB_0191275 Peptide, zgc:194446 Peptide, sepiapterin reductase Peptide, Sepiapterin reductase Peptide, sepiapterin reductase L homeolog Peptide, sepiapterin reductase b Peptide, SPR Peptide, Spr Peptide, Sptr Peptide, spr.L Peptide, sprE Peptide, CpipJ_CPIJ000511 Peptide, sr Peptide, spr Peptide, sprb Peptide
- Background
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This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Alias Symbols: SDR38C1
Protein Interaction Partner: CAMK2G
Protein Size: 261 - Molecular Weight
- 28 kDa
- Gene ID
- 6697
- NCBI Accession
- NM_003124, NP_003115
- UniProt
- P35270
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