Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Peptide
STAT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all STAT1 products
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STAT1 antibody (Catalog #: ARP38934_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- Synonyms
- CANDF7 Peptide, ISGF-3 Peptide, STAT91 Peptide, 2010005J02Rik Peptide, AA408197 Peptide, XStat1 Peptide, STAT4 Peptide, DD6G4-4 Peptide, STAT Peptide, STAT1 Peptide, dZ182H3.3 Peptide, si:by134g18.2 Peptide, si:by51f19.1 Peptide, si:dz182h3.3 Peptide, si:dz199m19.1 Peptide, si:dz73o4.2 Peptide, stat1 Peptide, signal transducer and activator of transcription 1 Peptide, signal transducer and activator of transcription 1 L homeolog Peptide, signal transducer and activator of transcription 1, 91kDa Peptide, signal transducer and activator of transcription 4 Peptide, signal transducer and activator of transcription 1a Peptide, STAT1 Peptide, Stat1 Peptide, stat1.L Peptide, stat4 Peptide, stat1a Peptide
- Background
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STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.Western blots using four different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: DKFZp686B04100, ISGF-3, STAT91, CANDF7
Protein Interaction Partner: CREBBP,GNB2L1,KIT,NMI,STAT1,STAT1,SYK,CREBBP,EP300,GNB2L1,NMI,SYK,ADRA1B,AKT1,BMX,BRCA1,CAMK2D,CAMK2G,CCR1,CCR5,CREBBP,CSE1L,CSF2RB,CXCR4,DUSP3,EGFR,EIF1AD,EIF2AK2,ELP2,EP300,FADD,FANCC,FGFR3,FGFR4,FOS,FYN,GNB2L1,GTF2I,HSF1,IFNAR2,IFNGR1,IL27RA,IL2RB,IL2RG,IRF1,IRF2,IRF9,JAK1,JAK2,JUN,KDR,KIT,KPNA1,KPNA6,LCK,LMO2,MAPK14,MCM3,MCM5,MDK,NMI,PDGFRA,PDGFRB,PIAS1,PRKCD,PRMT1,PTK2,PTPN11,PTPN2,RAC1,RELA,RPS6KA5,SRC,STAT1,STAT2,STAT3,STAT5A,STAT5B,SUMO4,SYK,TNFRSF1A,TNFRSF1B,TRADD,TYK2,UBE2I,VDR,XPO1,ZNF467,BRCA1,C20orf185,CREBBP,EGFR,EIF1AD,EIF2AK2,ELP2,EP300,FANCC,GNB2L1,GTF2I,HSF1,IFNAR2,IL27RA,IL2RB,IRF1,IRF9,JUN,KIT,KPNA1,KPNA2,LMO2,MCM5,MTOR,NMI,PIAS1,PRKCD,PTK2,RNF11,SRC,STAT1,STAT2,STAT2,STAT3,TNFRSF1A,TRADD,TYK2,VDR
Protein Size: 750 - Molecular Weight
- 87 kDa
- Gene ID
- 6772
- NCBI Accession
- NM_007315, NP_009330
- UniProt
- P42224
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