STEAP Family Member 3, Metalloreductase (STEAP3) Peptide
STEAP3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all STEAP3 products
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STEAP3 antibody (Catalog #: ARP43515_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- Synonyms
- STEAP3 Peptide, 1010001D01Rik Peptide, Tsap6 Peptide, pHyde Peptide, AHMIO2 Peptide, STMP3 Peptide, TSAP6 Peptide, dudlin-2 Peptide, STEAP3 metalloreductase Peptide, STEAP family member 3 Peptide, STEAP3 Peptide, steap3 Peptide, Steap3 Peptide
- Background
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AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: BNIP3L,PKMYT1,TPT1,BNIP3L,PKMYT1
Protein Size: 498 - Molecular Weight
- 56 kDa
- Gene ID
- 55240
- NCBI Accession
- NM_182915, NP_878919
- UniProt
- A8K6E3
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