Suppressor of Fused Homolog (SUFUH) (Middle Region) Peptide
SUFUH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SUFUH products
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SUFU antibody (Catalog #: ARP33018_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Synonyms
- CG6054 Peptide, Dmel\\CG6054 Peptide, SU(FU) Peptide, SUFU Peptide, Su(Fu) Peptide, SuFu Peptide, Sufu Peptide, su(fu) Peptide, sufu Peptide, Xsufu Peptide, sufuh Peptide, sufuxl Peptide, PRO1280 Peptide, SUFUH Peptide, SUFUXL Peptide, Su(fu) Peptide, dre Peptide, fi39e05 Peptide, wu:fi39e05 Peptide, 2810026F04Rik Peptide, b2b273Clo Peptide, Suppressor of fused Peptide, SUFU negative regulator of hedgehog signaling L homeolog Peptide, SUFU negative regulator of hedgehog signaling Peptide, suppressor of fused homolog (Drosophila) Peptide, Su(fu) Peptide, sufu.L Peptide, SUFU Peptide, sufu Peptide, Sufu Peptide
- Background
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SUFU is a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes. SUFU encodes a component of the sonic hedgehog (SHH, MIM 600725)/patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRO1280, SUFUH, SUFUXL
Protein Interaction Partner: BTRC,GLI1,GLI2,GLI3,GLIS3,HMGA1,HNRNPA1,LGALS3,MAPKSP1,MID1IP1,NCOA3,PEX26,PIAS1,QPRT,RBPJ,RCN3,RNF19A,SAP18,SETDB1,STK36,SUFU,ZNF219,ZNF263,ZNF446,ZNF764,GLI1,GLI2,GLI3,GLIS3,MID1IP1,PEX26,QPRT,RCN3,SUFU,ZNF263,ZNF446,ZNF764
Protein Size: 484 - Molecular Weight
- 54 kDa
- Gene ID
- 51684
- NCBI Accession
- NM_016169, NP_057253
- UniProt
- Q9UMX1
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