TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) Peptide
TBC1D10C
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all Carabin (TBC1D10C) products
- Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TBC1D10C antibody (Catalog #: ARP55893_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
- Synonyms
- CARABIN Peptide, EPI64C Peptide, 1810062O14Rik Peptide, AI428527 Peptide, RGD1311490 Peptide, TBC1 domain family member 10C Peptide, TBC1 domain family, member 10c Peptide, TBC1 domain family, member 10C Peptide, TBC1D10C Peptide, Tbc1d10c Peptide
- Background
-
TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].
Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN
Protein Interaction Partner: PPP3R2
Protein Size: 446 - Molecular Weight
- 50 kDa
- Gene ID
- 374403
- NCBI Accession
- NM_198517, NP_940919
- UniProt
- Q8IV04
-
You are here:
