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Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) Peptide

TCF7L2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN984910
  • Target See all TCF7L2 products
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- TCF7L2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    Synonyms
    TCF4B Peptide, TCF4E Peptide, Tcf-4 Peptide, Tcf4 Peptide, mTcf-4B Peptide, mTcf-4E Peptide, tcf4 Peptide, XTCF-4 Peptide, tcf4e Peptide, TCF4 Peptide, TCF-4 Peptide, TCFL2 Peptide, transcription factor 7 like 2 Peptide, transcription factor 7-like 2 Peptide, transcription factor 7 like 2, T cell specific, HMG box Peptide, transcription factor 7 like 2 L homeolog Peptide, transcription factor 7-like 2 (T-cell specific, HMG-box) Peptide, TCF7L2 Peptide, LOC100545943 Peptide, Tcf7l2 Peptide, tcf7l2 Peptide, tcf7l2.L Peptide
    Background
    This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

    Alias Symbols: TCF4, TCF-4

    Protein Size: 619
    Molecular Weight
    51 kDa
    Gene ID
    6934
    NCBI Accession
    XM_005270084, XP_005270141
    UniProt
    Q9NQB0
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