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Transglutaminase 1, Keratinocyte (TGM1) (N-Term) Peptide

TGM1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985037
  • Target See all TGM1 products
    TGM1 (Transglutaminase 1, Keratinocyte (TGM1))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TGM1 antibody (Catalog #: ARP41713_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TGM1 (Transglutaminase 1, Keratinocyte (TGM1))
    Synonyms
    TGM1 Peptide, ARCI1 Peptide, ICR2 Peptide, KTG Peptide, LI Peptide, LI1 Peptide, TGASE Peptide, TGK Peptide, 2310004J08Rik Peptide, Tgase1 Peptide, transglutaminase 1 Peptide, transglutaminase 1, K polypeptide Peptide, Tgm1 Peptide, TGM1 Peptide
    Background
    TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ICR2, KTG, LI, LI1, TGASE, TGK

    Protein Interaction Partner: RARRES3,HSPB1,MDK,RARRES3,SEMG1,SEMG2

    Protein Size: 817
    Molecular Weight
    90 kDa
    Gene ID
    7051
    NCBI Accession
    NM_000359, NP_000350
    UniProt
    P22735
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