TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) Peptide
Tiparp
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Tiparp products
- Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TIPARP antibody (Catalog #: ARP33763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
- Synonyms
- TIPARP Peptide, fc03g05 Peptide, sb:cb841 Peptide, si:dkey-33k14.4 Peptide, wu:fc03g05 Peptide, zgc:153056 Peptide, ddf1 Peptide, parp7 Peptide, parp-1 Peptide, parp-7 Peptide, ARTD14 Peptide, PARP7 Peptide, pART14 Peptide, AW558171 Peptide, RM1 Peptide, TCDD inducible poly(ADP-ribose) polymerase Peptide, TCDD-inducible poly(ADP-ribose) polymerase Peptide, TCDD-inducible poly [ADP-ribose] polymerase Peptide, TIPARP Peptide, tiparp Peptide, LOC100018933 Peptide, Tiparp Peptide
- Background
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TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
Alias Symbols: DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, pART14
Protein Interaction Partner: ATM,XRN2
Protein Size: 657 - Molecular Weight
- 76 kDa
- Gene ID
- 25976
- NCBI Accession
- NM_015508, NP_056323
- UniProt
- Q7Z3E1
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