Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide

Details for Product No. ABIN985225, Supplier: Log in to see
Protein Name
  • ERIS
  • MITA
  • MPYS
  • NET23
  • STING
  • 2610307O08Rik
  • Mita
  • RGD1562552
  • transmembrane protein 173
  • TMEM173
  • Tmem173
Protein Region
Middle Region
Origin
Human
4
2
1
1
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-TMEM173 antibody (Transmembrane Protein 173) (Middle Region) (ABIN2783202)
Sequence DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
Characteristics This is a synthetic peptide designed for use in combination with anti-TMEM173 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Alias Symbols: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING

Protein Size: 379
Molecular Weight 42 kDa
Gene ID 340061
NCBI Accession NM_198282, NP_938023
UniProt Q86WV6
Research Area Immunology, Cytokines, Innate Immunity
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.