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Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Peptide

TNFRSF10B Reactivity: Human, Drosophila melanogaster Host: Synthetic BP, WB
Catalog No. ABIN985299
  • Target See all TNFRSF10B products
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Origin
    Human, Drosophila melanogaster
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TNFRSF10B antibody (Catalog #: AVARP00032_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Synonyms
    TNFRSF10B Peptide, dr5 Peptide, cd262 Peptide, killer Peptide, trick2 Peptide, trickb Peptide, xDR-M1 Peptide, xDR-M2 Peptide, ztnfr9 Peptide, trailr2 Peptide, trick2a Peptide, trick2b Peptide, CD262 Peptide, DR5 Peptide, KILLER Peptide, KILLER/DR5 Peptide, TRAIL-R2 Peptide, TRAILR2 Peptide, TRICK2 Peptide, TRICK2A Peptide, TRICK2B Peptide, TRICKB Peptide, ZTNFR9 Peptide, Ly98 Peptide, MK Peptide, tumor necrosis factor receptor superfamily, member 10b Peptide, tumor necrosis factor receptor superfamily member 10b S homeolog Peptide, tumor necrosis factor receptor superfamily member 10b L homeolog Peptide, tumor necrosis factor receptor superfamily member 10b Peptide, TNF receptor superfamily member 10b Peptide, Tnfrsf10b Peptide, TNFRSF10B Peptide, tnfrsf10b.S Peptide, tnfrsf10b.L Peptide, tnfrsf10b Peptide
    Background
    The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

    Alias Symbols: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9

    Protein Interaction Partner: PRKCD,RARA,TP53,CASP8,CFLAR,FADD,MADD,RIPK1,TNFRSF10A,TNFRSF10D,TNFSF10,TRADD,ARHGDIA,BID,CASP10,CASP8,CFLAR,EZR,FADD,FAS,FASLG,MAPK8,MSN,RHOA,RIPK1,TIMM50,TNFRSF1A,TNFSF10,TNFSF10,TRADD

    Protein Size: 440
    Molecular Weight
    42 kDa
    Gene ID
    8795
    NCBI Accession
    NM_003842, NP_003833
    UniProt
    O14763
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