Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Peptide
-
- Target See all TNFRSF10B products
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Origin
- Human, Drosophila melanogaster
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFRSF10B antibody (Catalog #: AVARP00032_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Synonyms
- TNFRSF10B Peptide, dr5 Peptide, cd262 Peptide, killer Peptide, trick2 Peptide, trickb Peptide, xDR-M1 Peptide, xDR-M2 Peptide, ztnfr9 Peptide, trailr2 Peptide, trick2a Peptide, trick2b Peptide, CD262 Peptide, DR5 Peptide, KILLER Peptide, KILLER/DR5 Peptide, TRAIL-R2 Peptide, TRAILR2 Peptide, TRICK2 Peptide, TRICK2A Peptide, TRICK2B Peptide, TRICKB Peptide, ZTNFR9 Peptide, Ly98 Peptide, MK Peptide, tumor necrosis factor receptor superfamily, member 10b Peptide, tumor necrosis factor receptor superfamily member 10b S homeolog Peptide, tumor necrosis factor receptor superfamily member 10b L homeolog Peptide, tumor necrosis factor receptor superfamily member 10b Peptide, TNF receptor superfamily member 10b Peptide, Tnfrsf10b Peptide, TNFRSF10B Peptide, tnfrsf10b.S Peptide, tnfrsf10b.L Peptide, tnfrsf10b Peptide
- Background
-
The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Alias Symbols: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Protein Interaction Partner: PRKCD,RARA,TP53,CASP8,CFLAR,FADD,MADD,RIPK1,TNFRSF10A,TNFRSF10D,TNFSF10,TRADD,ARHGDIA,BID,CASP10,CASP8,CFLAR,EZR,FADD,FAS,FASLG,MAPK8,MSN,RHOA,RIPK1,TIMM50,TNFRSF1A,TNFSF10,TNFSF10,TRADD
Protein Size: 440 - Molecular Weight
- 42 kDa
- Gene ID
- 8795
- NCBI Accession
- NM_003842, NP_003833
- UniProt
- O14763
-