Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (C-Term) Peptide
TNFRSF13C
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TNFRSF13C products
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PGISDATAPA WPPPGEDPGT TPPGHSVPVP ATELGSTELV TTKTAGPEQQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFRSF13C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- Synonyms
- RGD1560810 Peptide, TNFRSF13C Peptide, BAFF-R Peptide, BAFFR Peptide, BROMIX Peptide, CD268 Peptide, CVID4 Peptide, prolixin Peptide, 2010006P15Rik Peptide, Baffr Peptide, Bcmd Peptide, Bcmd-1 Peptide, Bcmd1 Peptide, Lvis22 Peptide, TNF receptor superfamily member 13C Peptide, uncharacterized LOC746611 Peptide, tumor necrosis factor receptor superfamily, member 13c Peptide, TNFRSF13C Peptide, Tnfrsf13c Peptide, LOC746611 Peptide
- Background
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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Alias Symbols: BAFF-R, BAFFR, CD268, MGC138235, CVID4, BROMIX, prolixin
Protein Size: 184 - Molecular Weight
- 20 kDa
- Gene ID
- 115650
- NCBI Accession
- NM_052945, NP_443177
- UniProt
- Q96RJ3
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