Tumor Protein P53 Inducible Protein 3 (TP53I3) (C-Term) Peptide
TP53I3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TP53I3 products
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SKLLFKRGSL ITSLLRSRDN KYKQMLVNAF TEQILPHFST EGPQRLLPVL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TP53I3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
- Synonyms
- MGC82892 Peptide, MGC146409 Peptide, PIG3 Peptide, tumor protein p53 inducible protein 3 Peptide, tumor protein p53 inducible protein 3 S homeolog Peptide, Tp53I3 Peptide, quinone oxidoreductase PIG3 Peptide, TP53I3 Peptide, tp53i3.S Peptide, tp53i3 Peptide, tp53I3 Peptide
- Background
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The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
Alias Symbols: PIG3
Protein Size: 243 - Molecular Weight
- 26 kDa
- Gene ID
- 9540
- NCBI Accession
- NM_001206802
- UniProt
- B4DMQ7
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