TRAF3 Interacting Protein 2 (TRAF3IP2) (N-Term) Peptide
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- Target See all TRAF3IP2 products
- TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IPVEVDESEP YPSQLLKPIP EYSPEEESEP PAPNIRNMAP NSLSAPTMLH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRAF3IP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))
- Synonyms
- ACT1 Peptide, C6orf2 Peptide, C6orf4 Peptide, C6orf5 Peptide, C6orf6 Peptide, CIKS Peptide, PSORS13 Peptide, AI429613 Peptide, Act1 Peptide, RGD1304768 Peptide, C6ORF4 Peptide, t3jam Peptide, traf3ip2 Peptide, TRAF3IP2 Peptide, MGC134034 Peptide, TRAF3 interacting protein 2 Peptide, Traf3 interacting protein 2 Peptide, adapter protein CIKS Peptide, TRAF3 interacting protein 2 L homeolog Peptide, TRAF3IP2 Peptide, Traf3ip2 Peptide, LOC100473939 Peptide, traf3ip3.L Peptide, traf3ip3 Peptide
- Background
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This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Alias Symbols: ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581, PSORS13
Protein Size: 574 - Molecular Weight
- 65 kDa
- Gene ID
- 10758
- NCBI Accession
- NM_147200, NP_671733
- UniProt
- O43734
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