Trafficking Protein Particle Complex 2 (TRAPPC2) (Middle Region) Peptide
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- Target See all TRAPPC2 products
- TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRAPPC2 antibody (Catalog #: ARP50568_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))
- Synonyms
- MIP2A Peptide, SEDL Peptide, SEDT Peptide, TRAPPC2P1 Peptide, TRS20 Peptide, ZNF547L Peptide, hYP38334 Peptide, 1110066L09Rik Peptide, 1810064C02Rik Peptide, AW496358 Peptide, MIP-2A Peptide, Sedl Peptide, RGD1306925 Peptide, trafficking protein particle complex 2 Peptide, trafficking protein particle complex 2 S homeolog Peptide, trappc2 Peptide, TRAPPC2 Peptide, Trappc2 Peptide, trappc2.S Peptide
- Background
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TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.
Alias Symbols: MIP-2A, SEDL, SEDT, TRS20, ZNF547L, hYP38334, MIP2A, TRAPPC2P1
Protein Interaction Partner: CLIC1,CLIC2,CLIC1,CLIC2,ENO1,JOSD2
Protein Size: 140 - Molecular Weight
- 16 kDa
- Gene ID
- 6399
- NCBI Accession
- NM_014563, NP_055378
- UniProt
- O14582
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