TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) Peptide
TRIOBP
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all TRIOBP products
- TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIOBP antibody (Catalog #: ARP34718_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
- Synonyms
- tara Peptide, DFNB28 Peptide, TARA Peptide, dJ37E16.4 Peptide, AI428493 Peptide, EST478828 Peptide, Tara Peptide, mKIAA1662 Peptide, TRIO and F-actin binding protein Peptide, TRIO and F-actin-binding protein Peptide, TRIO and F-actin binding protein L homeolog Peptide, TRIO and F-actin binding protein-like Peptide, TRIOBP Peptide, LOC100354753 Peptide, triobp.L Peptide, TRIOBPL Peptide, Triobp Peptide
- Background
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TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
Protein Interaction Partner: VIM,HECTD3,UBC,VIM
Protein Size: 431 - Molecular Weight
- 47 kDa
- Gene ID
- 11078
- NCBI Accession
- NM_138632, NP_619538
- UniProt
- A6NID1
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