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Tissue Specific Transplantation Antigen P35B (TSTA3) (N-Term) Peptide

TSTA3 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN985700
  • Target See all TSTA3 products
    TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TSTA3 antibody (Catalog #: ARP58679_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
    Synonyms
    FX Peptide, P35B Peptide, SDR4E1 Peptide, AI256181 Peptide, Tstap35b Peptide, p35b Peptide, sdr4e1 Peptide, TSTA3 Peptide, zgc:101805 Peptide, si:dkey-235d18none Peptide, Fx Peptide, tissue specific transplantation antigen P35B Peptide, tissue specific transplantation antigen P35B L homeolog Peptide, TSTA3 Peptide, Tsta3 Peptide, tsta3 Peptide, tsta3.L Peptide
    Background
    Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

    Alias Symbols: FX, P35B, SDR4E1

    Protein Size: 321
    Molecular Weight
    35 kDa
    Gene ID
    7264
    NCBI Accession
    NM_003313, NP_003304
    UniProt
    Q13630
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