Tissue Specific Transplantation Antigen P35B (TSTA3) (N-Term) Peptide
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- Target See all TSTA3 products
- TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TSTA3 antibody (Catalog #: ARP58679_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
- Synonyms
- FX Peptide, P35B Peptide, SDR4E1 Peptide, AI256181 Peptide, Tstap35b Peptide, p35b Peptide, sdr4e1 Peptide, TSTA3 Peptide, zgc:101805 Peptide, si:dkey-235d18none Peptide, Fx Peptide, tissue specific transplantation antigen P35B Peptide, tissue specific transplantation antigen P35B L homeolog Peptide, TSTA3 Peptide, Tsta3 Peptide, tsta3 Peptide, tsta3.L Peptide
- Background
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Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Alias Symbols: FX, P35B, SDR4E1
Protein Size: 321 - Molecular Weight
- 35 kDa
- Gene ID
- 7264
- NCBI Accession
- NM_003313, NP_003304
- UniProt
- Q13630
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