Tubby Homolog (TUB) (N-Term) Peptide
TUB
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all TUB products
- TUB (Tubby Homolog (TUB))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TUB antibody (Catalog #: ARP33467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TUB (Tubby Homolog (TUB))
- Synonyms
- rd5 Peptide, tubby Peptide, MGC79522 Peptide, TUB Peptide, MGC80126 Peptide, MGC84061 Peptide, tub Peptide, tubby bipartite transcription factor Peptide, tubby bipartite transcription factor S homeolog Peptide, tub Peptide, TUB Peptide, tub.S Peptide, Tub Peptide
- Background
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TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: rd5
Protein Interaction Partner: ABL1,GNAQ,GRB2,IRS1,JAK2,LCK,PIK3R1,PLCG1,SRC,ABL1,JAK2,PLCG1
Protein Size: 561 - Molecular Weight
- 62 kDa
- Gene ID
- 7275
- NCBI Accession
- NM_003320, NP_003311
- UniProt
- P50607
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