Netrin receptor UNC5B (UNC5B) (Middle Region) Peptide
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- Target See all UNC5B products
- UNC5B (Netrin receptor UNC5B (UNC5B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VVVALFVYRK NHRDFESDII DSSALNGGFQ PVNIKAARQD LLAVPPDLTS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UNC5C Antibody(ARP45508_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UNC5B (Netrin receptor UNC5B (UNC5B))
- Synonyms
- unc5h2 Peptide, 6330415E02Rik Peptide, A630020F16 Peptide, D10Bwg0792e Peptide, Unc5h2 Peptide, UNC5H2 Peptide, p53RDL1 Peptide, UNC5C Peptide, UNC5B Peptide, p53rdl1 Peptide, unc-5 netrin receptor B Peptide, unc-5 netrin receptor B L homeolog Peptide, unc5b Peptide, Unc5b Peptide, UNC5B Peptide, unc5b.L Peptide
- Background
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UNC5C belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin, they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
Alias Symbols: UNC5H3
Protein Interaction Partner: DAPK1,DAPK1,NTN1
Protein Size: 931 - Molecular Weight
- 103 kDa
- Gene ID
- 8633
- NCBI Accession
- NM_003728, NP_003719
- UniProt
- O08747
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