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Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (Middle Region) Peptide

WNT6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN986225
  • Target See all WNT6 products
    WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-WNT6 antibody (Catalog #: ARP46733_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
    Synonyms
    WNT6 Peptide, si:dkey-31m21.2 Peptide, Wnt6 Peptide, AA409270 Peptide, Wnt-6 Peptide, Xwnt-6 Peptide, wnt-6 Peptide, wnt6-A Peptide, xWnt6 Peptide, Wnt family member 6 Peptide, wingless-type MMTV integration site family, member 6b Peptide, wingless-type MMTV integration site family, member 6 Peptide, Wnt family member 6 S homeolog Peptide, WNT6 Peptide, Wnt6 Peptide, wnt6b Peptide, wnt6.S Peptide
    Background
    The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.

    Alias Symbols: -

    Protein Interaction Partner: PORCN

    Protein Size: 365
    Molecular Weight
    37 kDa
    Gene ID
    7475
    NCBI Accession
    NM_006522, NP_006513
    UniProt
    Q9Y6F9
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