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WW Domain Containing Transcription Regulator 1 (WWTR1) Peptide

WWTR1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN986242
  • Target See all WWTR1 products
    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-WWTR1 antibody (Catalog #: ARP32540_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
    Synonyms
    WWTR1 Peptide, TAZ Peptide, 2310058J06Rik Peptide, 2610021I22Rik Peptide, C78399 Peptide, Taz Peptide, WW domain containing transcription regulator 1 L homeolog Peptide, WW domain containing transcription regulator 1 Peptide, wwtr1.L Peptide, wwtr1 Peptide, WWTR1 Peptide, Wwtr1 Peptide
    Background
    TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.

    Alias Symbols: DKFZP586I1419, TAZ

    Protein Interaction Partner: NKX2-1,PAX3,RUNX1,SLC9A3R2,TEAD3,TEAD4,YWHAE,SLC9A3R2,TEAD3,TEAD4

    Protein Size: 400
    Molecular Weight
    44 kDa
    Gene ID
    25937
    NCBI Accession
    NM_015472, NP_056287
    UniProt
    Q9GZV5
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