Zinc Metalloproteinase, Ste24 (Zmpste24) Peptide
Zmpste24
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ZMPSTE24 (Zmpste24) products
- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ZMPSTE24 antibody (Catalog #: ARP46665_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
- Synonyms
- DDBDRAFT_0189115 Peptide, DDBDRAFT_0237846 Peptide, DDB_0189115 Peptide, DDB_0237846 Peptide, F2N1.21 Peptide, F2N1_21 Peptide, STE24 Peptide, FACE-1 Peptide, FACE1 Peptide, HGPS Peptide, PRO1 Peptide, Ste24p Peptide, A530043O15Rik Peptide, D030046F19 Peptide, Face-1 Peptide, MADB Peptide, fi45a02 Peptide, wu:fi45a02 Peptide, zgc:55655 Peptide, zinc metallopeptidase STE24 Peptide, zinc metallopeptidase STE24 L homeolog Peptide, CAAX prenyl protease Peptide, Peptidase family M48 family protein Peptide, zinc metallopeptidase, STE24 Peptide, zinc metallopeptidase, STE24 homolog Peptide, ZMPSTE24 Peptide, zmpste24.L Peptide, zmpste24 Peptide, ATSTE24 Peptide, Zmpste24 Peptide
- Background
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ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Size: 475 - Molecular Weight
- 55 kDa
- Gene ID
- 10269
- NCBI Accession
- NM_005857, NP_005848
- UniProt
- O75844
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