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WNK Lysine Deficient Protein Kinase 2 ELISA Kits (WNK2)
On www.antibodies-online.com are 1 WNK Lysine Deficient Protein Kinase 2 (WNK2) ELISA Kits from 1 different suppliers available. Additionally we are shipping WNK2 Antibodies (31) and WNK2 Proteins (3) and many more products for this protein. A total of 38 WNK2 products are currently listed.
Synonyms:
1810073P09Rik, ARABIDOPSIS THALIANA WITH NO K 2, ATWNK2, AW122246, ESTM15, mKIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, PROTEIN KINASE, RGD1307284, SDCCAG43, with no lysine (K) kinase 2, WNK2, X83337, ZIK3
list all ELISA KIts Gene Name GeneID UniProt
WNK2 65268 Q9Y3S1
Mouse WNK2 WNK2 75607 Q3UH66
Rat WNK2 WNK2 306811  

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Human WNK Lysine Deficient Protein Kinase 2 (WNK2) interaction partners

  1. WNK2 promoter methylation and silencing in gliomas is associated with increased JNK (show MAPK8 ELISA Kits) activation and MMP2 (show MMP2 ELISA Kits) expression and activity, thus explaining in part tumor cell invasion potential.

  2. Downregulation of WNK2 by promoter hypermethylation occurs early in Pancreatic ductal adenocarcinoma pathogenesis and may support tumor cell growth via the ERK-MAPK (show MAPK1 ELISA Kits) pathway.

  3. Wnk kinases are positive regulators of canonical Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling.

  4. results validate the WNK2 gene as a recurrent target for epigenetic silencing in glia-derived brain tumours and provide first mechanistic evidence for a tumour-suppressing role of WNK2 that is related to Rac1 signalling and tumour cell invasion and growth

  5. a role for WNK2 in the regulation of CCCs in the mammalian brain, with implications for both cell volume regulation and/or GABAergic signaling.

  6. epigenetic silencing, occasional deletion and point mutation, and functional assessment suggest that aberrations of WNK2 may contribute to unregulated tumor cell growth

  7. WNK2 is involved in the modulation of growth factor-induced cancer cell proliferation through the MEK1 (show MAP2K1 ELISA Kits)/ERK1/2 (show MAPK1/3 ELISA Kits) pathway.

  8. WNK2 controls a RhoA (show RHOA ELISA Kits)-mediated cross-talk mechanism that regulates the efficiency with which MEK1 (show MAP2K1 ELISA Kits) can activate ERK1/2 (show MAPK1/3 ELISA Kits) upon growth factor stimulation.

  9. Epigenetic silencing of the kinase tumor suppressor WNK2 is tumor-type and tumor-grade specific.

WNK2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytoplasmic serine-threonine kinase that contains cysteine in place of the lysine found at the conserved ATP-binding location in subdomain II of protein kinases. Since this protein does have kinase activity, it is possible that another lysine in the kinase subdomain I can substitute for the missing conserved lysine.

Alternative names and synonyms associated with WNK2

  • WNK lysine deficient protein kinase 2 (WNK2) Elisa Kit
  • serine/threonine-protein kinase WNK2 (WNK2) Elisa Kit
  • WNK lysine deficient protein kinase 2 (Wnk2) Elisa Kit
  • 1810073P09Rik Elisa Kit
  • ARABIDOPSIS THALIANA WITH NO K 2 Elisa Kit
  • ATWNK2 Elisa Kit
  • AW122246 Elisa Kit
  • ESTM15 Elisa Kit
  • mKIAA1760 Elisa Kit
  • NY-CO-43 Elisa Kit
  • P/OKcl.13 Elisa Kit
  • PRKWNK2 Elisa Kit
  • PROTEIN KINASE Elisa Kit
  • RGD1307284 Elisa Kit
  • SDCCAG43 Elisa Kit
  • with no lysine (K) kinase 2 Elisa Kit
  • WNK2 Elisa Kit
  • X83337 Elisa Kit
  • ZIK3 Elisa Kit

Protein level used designations for WNK2

WNK lysine deficient protein kinase 2 , antigen NY-CO-43 , mitogen-activated protein kinase kinase kinase , protein kinase lysine-deficient 2 , protein kinase with no lysine 2 , protein kinase, lysine deficient 2 , serine/threonine-protein kinase WNK2 , serologically defined colon cancer antigen 43 , kinase deficient protein

GENE ID SPECIES
415984 Gallus gallus
506520 Bos taurus
717275 Macaca mulatta
100544669 Meleagris gallopavo
821810 Arabidopsis thaliana
65268 Homo sapiens
75607 Mus musculus
306811 Rattus norvegicus
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