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Browse our anti-AKT (AKT1) Antibodies

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 Antibodies (AKT1)
On are 1101 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antibodies from 43 different suppliers available. Additionally we are shipping AKT Kits (49) and AKT Proteins (37) and many more products for this protein. A total of 1288 AKT products are currently listed.
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

All available anti-AKT Antibodies

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Top referenced anti-AKT Antibodies

  1. Chicken Polyclonal AKT Primary Antibody for EIA, WB - ABIN401485 : Pino, Alata, Dedonder, Jouvet, Sakota, Sekiya: Photon induced isomerization in the first excited state of the 7-azaindole-(H2O)3 cluster. in Physical chemistry chemical physics : PCCP 2011 (PubMed)
    Show all 7 references for ABIN401485

  2. Human Polyclonal AKT Primary Antibody for DB, EIA - ABIN358371 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 5 references for ABIN358371

  3. Human Monoclonal AKT Primary Antibody for EIA, IF - ABIN400786 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for ABIN400786

  4. Chimpanzee Monoclonal AKT Primary Antibody for EIA, IF - ABIN400785 : Staal: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. in Proceedings of the National Academy of Sciences of the United States of America 1987 (PubMed)
    Show all 4 references for ABIN400785

  5. Human Monoclonal AKT Primary Antibody for EIA, IHC (fro) - ABIN400791 : Lawlor, Alessi: PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? in Journal of cell science 2001 (PubMed)
    Show all 4 references for ABIN400791

  6. Human Polyclonal AKT Primary Antibody for IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)
    Show all 2 references for ABIN725195

  7. Chicken Polyclonal AKT Primary Antibody for EIA, IHC (fro) - ABIN117897 : Alessi: Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture. in Biochemical Society transactions 2001 (PubMed)
    Show all 2 references for ABIN117897

  8. Human Polyclonal AKT Primary Antibody for DB - ABIN650890 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. in PLoS ONE 2010 (PubMed)

More Antibodies against AKT Interaction Partners

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  2. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  3. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  4. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (show GRIN1 Antibodies) localization, and postsynaptic membrane elaboration

  5. Tsc2 (show TSC2 Antibodies) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (show TSC2 Antibodies) mutants, leading to the hypothesis that Tsc2 (show TSC2 Antibodies) and Akt might work via the same genetic pathway to regulate synapse growth.

  6. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  7. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (show PTEN Antibodies) and microRNA bantam.

  8. Overexpression of Akt enhanced Sindbis virus replication.

  9. Perturbation of the Akt/Gsk3-beta (show GSK3b Antibodies) signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

  10. dAkt activation under wild-type conditions is defined by feedback inhibition that depends on TOR Complex 1

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (show FNTA Antibodies), which further represses the activity of K(+) channel (show KCNC4 Antibodies) AKT1 in Arabidopsis.

  2. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  3. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  4. These findings provide further insights into the signaling network consisting of CBL (show CBL Antibodies)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  5. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  6. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  7. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  8. CIPK23 directly phosphorylates the K+ transporter AKT1

  9. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (show CA2 Antibodies)+)-dependent manner, connecting the Ca(2 (show CA2 Antibodies)+) signal to K(+) uptake through activation of a K(+) channel (show KCNC4 Antibodies).

  10. AtAKT1 mediates K+ absorption at high concentrations, and remains active in the presence of NH4+ although activity is reduced.

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. Data show that RNA silencing of CCN family member 1 (show CYR61 Antibodies) protein (CCN1 (show CCNA2 Antibodies)) inhibits retinal neovascularization (RNV) by inhibiting phosphoinositide 3-kinase (PI3K)/AKT protein signaling in mouse pup model of oxygen-induced retinopathy (OIR).

  2. rescued the hepatic regenerative capability in Akt1-deficient and Akt2 (show AKT2 Antibodies)-deficient mice

  3. While combined Akt1 and Akt3 deletion in adult mice is tolerated, combined Akt1 and Akt2 deletion induced rapid mortality involving glucose metabolism problems. ACT1-null mice are not resistant to diethylnitrosamine hepatocarcinogenesis.

  4. ShRNA knockdown (kd) of AKT1 prevents phosphorylation and subsequent degradation of nuclear lamins.

  5. Our study suggests that Ab25-35 induces autophagy and the PI3K/AKT/mTOR (show FRAP1 Antibodies)/p70S6K (show RPS6KB1 Antibodies) pathway is involved in the process, which improves our understanding of the pathogenesis of Alzheimer's disease and provides an additional model for AD research

  6. We propose that targeted inhibition of PTEN (show PTEN Antibodies) and hyperactivation of AKT triggers a checkpoint for the elimination of autoreactive B cells and represents a new strategy to overcome drug resistance in human pre-B acute lymphoblastic leukemia .

  7. Expression of activated AKT1 resulted in highly metastatic melanomas with lung and brain metastases.

  8. results support the hypothesis that inhibiting dephosphorylation of pAKT may be one of the pathways by which LAT (show LAT Antibodies) protects cells against apoptosis

  9. androstenedione administration increased Akt1 and PKC zeta (show PRKCZ Antibodies) phosphorylation in the muscle tissue of C57BL6 mice.

  10. Akt-dependent Girdin (show CCDC88A Antibodies) phosphorylation regulates repair processes after acute myocardial infarction.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. One of the mechanisms was TF3 inactivated Akt/mTOR (show FRAP1 Antibodies)/p70S6K (show RPS6KB1 Antibodies)/4E-BP1 (show EIF4EBP1 Antibodies) pathway and Akt/c-Myc (show MYC Antibodies) pathway

  2. These data suggest that targeting the IL-8 (show IL8 Antibodies)/AKT1 signaling pathway and DNMT1 (show DNMT1 Antibodies) may provide a potential therapeutic approach for blocking NPC (show NPC1 Antibodies) metastasis.

  3. critical pathophysiologic event in the evolution of HER2 (show ERBB2 Antibodies)-amplified cancers is the loss of the input signals that normally drive TORC2 (show CRTC2 Antibodies) signaling, repositioning it under Akt dependency, and fundamentally altering the role of HER3 (show ERBB3 Antibodies)

  4. Data show that cytoplasmic cyclin-dependent kinase inhibitor p27 (show CDKN1B Antibodies) is preferentially observed in primary non-small cell lung cancer (NSCLC) with activated proto-oncogene (show RAB1A Antibodies) proteins c-akt1 and predicts poor survival.

  5. High AKT expression is associated with cancer.

  6. Data indicate the role of tropomyosin-related kinase-B (TrkB (show NTRK2 Antibodies)) in activation of the interleukin-6 (show IL6 Antibodies)/Janus kinase 2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) transcription factor and PI3 kinase (show PIK3CA Antibodies)/c-AKT proto-oncogene (show RAB1A Antibodies) protein pathway in breast cancer.

  7. Data show that RNA silencing of CCN family member 1 (show CYR61 Antibodies) protein (CCN1 (show CCNA2 Antibodies)) inhibits umbilical vein endothelial cell (HUVEC) proliferation under hypoxic conditions by inhibiting phosphoinositide 3-kinase (PI3K (show PIK3CA Antibodies))/AKT protein signaling.

  8. Akt has a role in several key steps of peripheral nervous system myelination, including axon wrapping and myelin sheath thickness.

  9. Data show that puquitinib mesylate (XC-302) induced autophagy in nasopharyngeal cancer cells CNE-2 by promoting cell autophagy and inhibits the phosphatidylinositol 3-Kinase (PI3K (show PIK3CA Antibodies))/AKT protein/TOR (show RORC Antibodies) serine-threonine kinases (mTOR (show FRAP1 Antibodies)) signaling pathway.

  10. this study highlights the molecular basis for posttranslational modifications of Gata3 (show GATA3 Antibodies) that control the regulation of IFNgamma expression in memory Th2 cells.

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  2. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  3. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  4. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  5. findings show that megalin (show LRP2 Antibodies) is the sensor that determines whether cells will be protected or injured by albumin (show ALB Antibodies); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  6. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  7. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

  8. in VSMCs exposed to hyperglycemia, IGF-I (show IGF1 Antibodies) stimulation of Shc (show SHC1 Antibodies) facilitates the transfer of Grb2 (show GRB2 Antibodies) to p85 (show ARHGEF7 Antibodies) resulting in enhanced PI3K activation and AKT phosphorylation leading to enhanced cell proliferation and migration

  9. There was no correlation of infarct size with expression or phosphorylation of AKT in ischemic postconditioning.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (show CTNNB1 Antibodies) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (show CAV1 Antibodies) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (show TGM2 Antibodies) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (show GSK3b Antibodies), and NF-kappaB (show NFKB1 Antibodies).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (show NOX1 Antibodies), reactive oxygen species, and PI3-kinase (show PIK3CA Antibodies) in stimulated NO release.

  6. PI3K/Akt and p53 (show TP53 Antibodies) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (show FRAP1 Antibodies), p70S6K (show RPS6KB1 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies).

  8. Gab1 (show GAB1 Antibodies) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (show NOS3 Antibodies) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (show NOS3 Antibodies) phosphorylation and suppresses tumor necrosis factor alpha (show TNF Antibodies)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 Antibodies) and activates mTOR (show FRAP1 Antibodies) and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT-independent manner

AKT (AKT1) Antigen Profile

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) antibody
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) antibody
  • CG4006 gene product from transcript CG4006-RA (Akt1) antibody
  • potassium channel AKT1 (KT1) antibody
  • thymoma viral proto-oncogene 1 (Akt1) antibody
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) antibody
  • akt antibody
  • akt-1 antibody
  • Akt/PKB antibody
  • akt1 antibody
  • ATAKT1 antibody
  • CG4006 antibody
  • CWS6 antibody
  • D-Akt antibody
  • dakt antibody
  • dAKT/dPKB antibody
  • dAkt/PKB antibody
  • dakt1 antibody
  • DAKT1/PKB antibody
  • Dmel\\CG4006 antibody
  • dPKB antibody
  • DRAC-PK antibody
  • DRAC-PK66 antibody
  • DRAC-PK85 antibody
  • F18A8.2 antibody
  • F18A8_2 antibody
  • K+ transporter 1 antibody
  • l(3)04226 antibody
  • l(3)89Bq antibody
  • p-Akt antibody
  • pAkt antibody
  • PKB antibody
  • PKB-ALPHA antibody
  • PKB/Akt antibody
  • PKB/dAKT antibody
  • PKBalpha antibody
  • PRKBA antibody
  • Rac antibody
  • RAC-ALPHA antibody
  • RacPK antibody
  • v-akt antibody
  • v-akt1 antibody
  • xAct antibody

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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