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Browse our anti-AKT (AKT1) Antibodies

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 Antibodies (AKT1)
On www.antibodies-online.com are 1159 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antibodies from 45 different suppliers available. Additionally we are shipping AKT Kits (56) and AKT Proteins (46) and many more products for this protein. A total of 1360 AKT products are currently listed.
Synonyms:
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

All available anti-AKT Antibodies

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Top referenced anti-AKT Antibodies

  1. Human Polyclonal AKT Primary Antibody for FACS, WB - ABIN652283 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for ABIN652283

  2. Human Monoclonal AKT Primary Antibody for EIA, IF - ABIN400786 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for ABIN400786

  3. Chimpanzee Monoclonal AKT Primary Antibody for EIA, IF - ABIN400784 : Staal: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. in Proceedings of the National Academy of Sciences of the United States of America 1987 (PubMed)
    Show all 4 references for ABIN400784

  4. Human Polyclonal AKT Primary Antibody for IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)
    Show all 3 references for ABIN725195

  5. Chicken Polyclonal AKT Primary Antibody for EIA, IHC (fro) - ABIN117897 : Lawlor, Alessi: PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? in Journal of cell science 2001 (PubMed)
    Show all 2 references for ABIN117897

  6. Human Polyclonal AKT Primary Antibody for DB, IF - ABIN650880 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. in PLoS ONE 2010 (PubMed)

More Antibodies against AKT Interaction Partners

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. subtle manipulation of foxo (show FOXO Antibodies) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  2. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  3. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  4. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  5. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (show GRIN1 Antibodies) localization, and postsynaptic membrane elaboration

  6. Tsc2 (show TSC2 Antibodies) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (show TSC2 Antibodies) mutants, leading to the hypothesis that Tsc2 (show TSC2 Antibodies) and Akt might work via the same genetic pathway to regulate synapse growth.

  7. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  8. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (show PTEN Antibodies) and microRNA bantam.

  9. Overexpression of Akt enhanced Sindbis virus replication.

  10. Perturbation of the Akt/Gsk3-beta (show GSK3b Antibodies) signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. CIPK23 and AtKC1 exhibit distinct effects; however, they act synergistically and balance K(+) uptake/leakage to modulate AKT1-mediated low potassium responses in Arabidopsis.

  2. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (show FNTA Antibodies), which further represses the activity of K(+) channel (show KCNC4 Antibodies) AKT1 in Arabidopsis.

  3. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  4. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  5. These findings provide further insights into the signaling network consisting of CBL (show CBL Antibodies)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  6. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  7. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  8. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  9. CIPK23 directly phosphorylates the K+ transporter AKT1

  10. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (show CA2 Antibodies)+)-dependent manner, connecting the Ca(2 (show CA2 Antibodies)+) signal to K(+) uptake through activation of a K(+) channel (show KCNC4 Antibodies).

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. A cell-culture study using an inhibitor of estrogen receptors and an in vivo experiment with ovariectomized mice suggested that the estrogenic activity of 8-PN contributed to recovery from disuse muscle atrophy through activation of an Akt phosphorylation pathway. These data strongly suggest that 8-PN is a naturally occurring compound that could be used as a nutritional supplement to aid recovery from disuse muscle atroph

  2. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  3. Data show that Akt/mTOR (show FRAP1 Antibodies) and MAPK (show MAPK1 Antibodies) pathways were activated in ovine pulmonary adenocarcinoma (OPA) lung and envelope (Env (show ERVW-1 Antibodies)) of Jaagsiekte sheep retrovirus (JSRV) transfected NIH 3T3 cells.

  4. Results suggest that SC79 compound activates Akt-Nrf2 (show NFE2L2 Antibodies) signaling to protect osteoblasts from dexamethasone (Dex).

  5. In conclusion, we have identified that ARL15 acts as an insulin (show INS Antibodies)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1 (show IRS1 Antibodies)/PDPK1 (show PDPK1 Antibodies)/AKT insulin (show INS Antibodies) pathway by interacting with its GAP ASAP2 (show ASAP2 Antibodies) and activating PDPK1 (show PDPK1 Antibodies). This research may provide new insights into GTPase (show RACGAP1 Antibodies)-mediated insulin (show INS Antibodies) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (show INS Antibodies) sensitizati

  6. Taken together, our findings imply that KLF15 possesses potential anti-hypertrophic and anti-fibrotic functions, possibly via regulation of cell death pathways and the inhibition of Akt/mTOR axis. KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases.

  7. Menin (show MEN1 Antibodies) binds on the promoter of Inhbb (show INHBB Antibodies) gene where it favours the recruitment of Ezh2 (show EZH2 Antibodies) via an indirect mechanism involving Akt-phosphorylation.

  8. A role of AKT in the regulatory T cell differentiation process. TGF-beta (show TGFB1 Antibodies) induces the phosphorylation of Akt in CD4 (show CD4 Antibodies)+ T cells.

  9. 4-PBA reverses autophagic dysfunction and improves insulin (show INS Antibodies) sensitivity in adipose tissue of obese mice via Akt/mTOR (show FRAP1 Antibodies) signaling partly, which could be regarded as novel opportunities for treatment of insulin (show INS Antibodies) resistance.

  10. These studies reveal a novel mechanism in which CYP2J2 (show CYP2J2 Antibodies) and epoxyeicosatrienoic acids enhanced Akt1 nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (show PIK3CA Antibodies)-Akt/PKB cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  2. Binding of PP2A (show PPP2R4 Antibodies) and Akt increased in response to cAMP or phosphatidic acid (PA), suggesting that their binding is directly responsible for the inactivation of Akt during decidualization.

  3. Results suggest that polymorphism of AKT1 locus is associated with risk of Parkinson's disease and that the G allele at rs2498799 may decrease the risk of Parkinson's disease in the North-eastern part of Han Chinese female population.

  4. Akt phosphorylates inversin (show INVS Antibodies) at amino acids 864-866 that are required not only for Akt interaction, but also for inversin (show INVS Antibodies) dimerization.

  5. In vitro study using human endothelial cells showed that prostaglandin E2 (PGE2) significantly increased MMP-2 (show MMP2 Antibodies) activity as well as tube formation. Inhibition of COX-2 (show COX2 Antibodies) and/or phosphorylated AKT suppressed MMP-2 (show MMP2 Antibodies) activity and endothelial tube formation suggesting involvement of PGE2 in regulation of MMP-2 (show MMP2 Antibodies) activity during angiogenesis.

  6. p-PTEN (show PTEN Antibodies), Akt, p-PDK1 (show PDK1 Antibodies), and p-GSK-3beta (show GSK3b Antibodies) were significantly downregulated after the knockdown of CK2alpha expression.

  7. the results show that EphA2 (show EPHA2 Antibodies) endows invasiveness of glioma stem cells in vivo in cooperation with Akt and regulates glioma stem cell properties

  8. We revealed that activation of the PI3K (show PIK3CA Antibodies)/Akt pathway was the main cause of impaired autophagy in ELK3 (show ELK3 Antibodies) KD. Our results suggest that targeting ELK3 (show ELK3 Antibodies) may be a potential approach to overcome doxorubicin resistance in breast cancer therapeutics.

  9. Our results show a miRNA editing activity trend aligning with cellular pathways closely associated to hypoxia, such as the VEGF (show VEGFA Antibodies) and PI3K (show PIK3CA Antibodies)/Akt pathways, providing important novel insights on this poorly elucidated phenomenon.

  10. CYT (show CYGB Antibodies)-Rx20 significantly reduced tumor growth of the implanted esophageal cancer cells accompanied by decreased Ki-67 (show MKI67 Antibodies), phospho-AKT, and phospho-STAT3 (show STAT3 Antibodies) expression.

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR (show FRAP1 Antibodies)-FOXO1 (show FOXO1 Antibodies) signaling and suppressing the activation of TLR4 (show TLR4 Antibodies) and/or NOD2 (show NOD2 Antibodies) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (show LRP2 Antibodies) is the sensor that determines whether cells will be protected or injured by albumin (show ALB Antibodies); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (show CTNNB1 Antibodies) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (show CAV1 Antibodies) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (show TGM2 Antibodies) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (show GSK3b Antibodies), and NF-kappaB (show NFKB1 Antibodies).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (show NOX1 Antibodies), reactive oxygen species, and PI3-kinase (show PIK3CA Antibodies) in stimulated NO release.

  6. PI3K/Akt and p53 (show TP53 Antibodies) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (show FRAP1 Antibodies), p70S6K (show RPS6KB1 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies).

  8. Gab1 (show GAB1 Antibodies) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (show NOS3 Antibodies) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (show NOS3 Antibodies) phosphorylation and suppresses tumor necrosis factor alpha (show TNF Antibodies)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 Antibodies) and activates mTOR (show FRAP1 Antibodies) and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT-independent manner

AKT (AKT1) Antigen Profile

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) antibody
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) antibody
  • CG4006 gene product from transcript CG4006-RA (Akt1) antibody
  • potassium channel AKT1 (KT1) antibody
  • thymoma viral proto-oncogene 1 (Akt1) antibody
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) antibody
  • akt antibody
  • akt-1 antibody
  • Akt/PKB antibody
  • akt1 antibody
  • ATAKT1 antibody
  • CG4006 antibody
  • CWS6 antibody
  • D-Akt antibody
  • dakt antibody
  • dAKT/dPKB antibody
  • dAkt/PKB antibody
  • dakt1 antibody
  • DAKT1/PKB antibody
  • Dmel\\CG4006 antibody
  • dPKB antibody
  • DRAC-PK antibody
  • DRAC-PK66 antibody
  • DRAC-PK85 antibody
  • F18A8.2 antibody
  • F18A8_2 antibody
  • K+ transporter 1 antibody
  • l(3)04226 antibody
  • l(3)89Bq antibody
  • p-Akt antibody
  • pAkt antibody
  • PKB antibody
  • PKB-ALPHA antibody
  • PKB/Akt antibody
  • PKB/dAKT antibody
  • PKBalpha antibody
  • POTASSIUM TRANSPORTER antibody
  • PRKBA antibody
  • Rac antibody
  • RAC-ALPHA antibody
  • RacPK antibody
  • v-akt antibody
  • v-akt1 antibody
  • xAct antibody

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

GENE ID SPECIES
100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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