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Browse our ATG13 Proteins (ATG13)

Full name:
Autophagy Related 13 Proteins (ATG13)
On are 5 Autophagy Related 13 (ATG13) Proteins from 4 different suppliers available. Additionally we are shipping ATG13 Antibodies (138) and ATG13 Kits (1) and many more products for this protein. A total of 150 ATG13 products are currently listed.
1110053A20Rik, D2Ertd391e, Harbi1, Harbi1l, KIAA0652, PARATARG8, RGD1310685, zgc:63526
list all proteins Gene Name GeneID UniProt
ATG13 9776 O75143
ATG13 51897 Q91YI1
Rat ATG13 ATG13 362164  

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ATG13 Proteins (ATG13) by Origin

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More Proteins for ATG13 Interaction Partners

Human Autophagy Related 13 (ATG13) interaction partners

  1. Structure of the human Atg13-Atg101 (show C12orf44 Proteins) HORMA heterodimer in the ULK1 (show ULK1 Proteins) complex that controls autophagy has been described.

  2. Specific affinity of the LC3 (show MAP1LC3A Proteins) isoforms to the Atg13 LC3 (show MAP1LC3A Proteins)-interacting region is required for proper autophagosome formation.

  3. In response to DNA damage, ULK1 (show ULK1 Proteins) and ULK2 (show ULK2 Proteins) are upregulated by p53 (show TP53 Proteins). The upregulation of ULK1 (show ULK1 Proteins) (ULK2 (show ULK2 Proteins))/ATG13 complex by p53 (show TP53 Proteins) is necessary for the sustained autophagy activity induced by DNA damage.

  4. The gene product is the functional homologue of yeast Atg13, and required for autophagy in mammalian cells.

  5. mTORC1 suppresses autophagy through direct regulation of the approximately 3-MDa ULK1-Atg13-FIP200 complex.

  6. The ULK-Atg13-FIP200 complexes are direct targets of mTOR (show FRAP1 Proteins) and important regulators of autophagy in response to mTOR (show FRAP1 Proteins) signaling.

  7. ATG13 and ULK1 are phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner, indicating that the ULK1.ATG13.FIP200 complex acts as a node for integrating incoming autophagy signals into autophagosome biogenesis.

  8. The identification of the novel protein, Atg101 (show C12orf44 Proteins), and the validation of Atg13 and Atg101 (show C12orf44 Proteins) as ULK1 (show ULK1 Proteins)-interacting proteins, suggests an Atg1 (show ULK1 Proteins) complex is involved in the induction of macroautophagy in mammalian cells.

  9. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200.

  10. Studies elucidated the inhibitory mechanism in which mTORC1 phosphorylates the autophagy regulatory complex containing unc-51-like kinase 1 (ULK1 (show ULK1 Proteins)), the mammalian Atg13 protein, and focal adhesion kinase interacting protein (show CIB1 Proteins) of 200 kD (FIP200).

Mouse (Murine) Autophagy Related 13 (ATG13) interaction partners

  1. ATG13 phosphorylation plays a crucial role in autophagy regulation.

  2. autophagy can be executed by mechanisms that are dependent or independent of the ULK1 (show ULK1 Proteins)/2-ATG13 interaction.

  3. Atg13-deficient embryos show growth retardation and myocardial growth defects.

ATG13 Protein Profile

Protein Summary

Autophagy factor required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex (By similarity).

Alternative names and synonyms associated with ATG13

  • autophagy related 13 (ATG13)
  • ATG13 autophagy related 13 homolog (S. cerevisiae) (ATG13)
  • ATG13 autophagy related 13 homolog (S. cerevisiae) (atg13)
  • autophagy related 13 (Atg13)
  • 1110053A20Rik protein
  • D2Ertd391e protein
  • Harbi1 protein
  • Harbi1l protein
  • KIAA0652 protein
  • PARATARG8 protein
  • RGD1310685 protein
  • zgc:63526 protein

Protein level used designations for Autophagy Related 13 Proteins (ATG13)

ATG13 autophagy related 13 homolog , autophagy-related protein 13 , harbinger transposase derived 1 , hypothetical protein

100050734 Equus caballus
507340 Bos taurus
393405 Danio rerio
423192 Gallus gallus
9776 Homo sapiens
483632 Canis lupus familiaris
51897 Mus musculus
362164 Rattus norvegicus
100171805 Pongo abelii
451155 Pan troglodytes
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