anti-Human CDK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CDK2 Antibody (supplied by: Log in to see )

Antigen
Cyclin-Dependent Kinase 2 (CDK2) Antibodies
  • p33(CDK2)
  • cinp
  • CINP
  • MGC84068
  • A630093N05Rik
  • wu:fa10c02
  • zgc:56598
  • zgc:77684
  • eg1
  • CDKN2
  • cdk2L
  • cyclin dependent kinase 2
  • cyclin dependent kinase 2 interacting protein
  • cyclin-dependent kinase 2 interacting protein S homeolog
  • cyclin-dependent kinase 2
  • cyclin-dependent kinase 2 S homeolog
  • CDK2
  • cinp
  • CINP
  • cinp.S
  • Cdk2
  • cdk2
  • cdk2.S
Epitope
C-Term
67
58
36
15
14
10
9
8
8
7
6
6
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
432
264
172
62
19
18
15
15
14
13
11
11
8
5
4
4
3
2
1
Host
Rabbit
331
159
1
Clonality
Polyclonal
Conjugate
This CDK2 antibody is un-conjugated
25
18
16
12
8
8
7
7
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
416
213
128
98
78
69
59
39
32
18
11
7
3
3
2
2
2
1
1
Supplier
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Catalog No. ABIN359658
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.221225 ABIN2172819 IF (p) IHC (p) WB Rabbit IgG AA 5-45 Log in to see Polyclonal 2
14.221225 ABIN337209 IHC (p) IP ELISA WB Mouse IgG Log in to see AN4-3
14.221225 ABIN214040 IHC (p) WB Rabbit IgG pThr160 Log in to see Polyclonal
14.221225 ABIN337208 IF IHC (p) IP ELISA WB Mouse IgG2, kappa Log in to see
14.221225 ABIN4297025 CyTOF ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see 1A6
14.221225 ABIN4297029 FACS ICC IF IHC IHC (p) WB Mouse IgG2a Log in to see 2D9
14.221225 ABIN218502 IF IHC (p) IP ELISA WB Rabbit C-Term Log in to see Polyclonal
14.221225 ABIN4297034 IHC (p) WB Mouse IgG2b Log in to see 2B6
14.221225 ABIN4297024 IHC IHC (p) WB Rabbit Log in to see Polyclonal
14.221225 ABIN4297021 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN3043472 IHC (p) WB Rabbit IgG AA 81-298 Log in to see Polyclonal 5
1 ABIN391746 FACS IHC (p) WB Rabbit Ig AA 230-260, C-Term Log in to see Polyclonal 5
1 ABIN196844 IHC (p) WB Rabbit pThr160 Log in to see Polyclonal 4
1 ABIN1881192 IHC (p) WB Rabbit AA 1-30, Thr14 Log in to see Polyclonal 5
1 ABIN400761 EIA IHC (p) IP WB Mouse IgG Log in to see 4i33
1 ABIN1106645 EIA FACS IF IHC (p) WB Mouse IgG1 Log in to see 1A6 1
1 ABIN1687224 IHC (p) Rabbit IgG C-Term Log in to see SP80
1 ABIN747008 IF (p) IHC (p) WB Rabbit IgG pThr160 Log in to see Polyclonal 1
1 ABIN757462 IF (p) IHC (p) WB Rabbit IgG pThr14 Log in to see Polyclonal 1
1 ABIN5556623 EIA IHC (fro) IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal

General

Antigen Cyclin-Dependent Kinase 2 (CDK2) Antibodies
Epitope C-Term
(67), (58), (36), (15), (14), (10), (9), (8), (8), (7), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(432), (264), (172), (62), (19), (18), (15), (15), (14), (13), (11), (11), (8), (5), (4), (4), (3), (2), (1)
Host Rabbit
(331), (159), (1)
Clonality
Polyclonal
Conjugate This CDK2 antibody is un-conjugated
(25), (18), (16), (12), (8), (8), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(416), (213), (128), (98), (78), (69), (59), (39), (32), (18), (11), (7), (3), (3), (2), (2), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-CDK2 Antibody

Target Details CDK2 Application Details Handling References for anti-CDK2 antibody (ABIN359658) Images
Specificity This antibody reacts to CDK2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CDK2.
Isotype Ig

Target Details CDK2

Product Details anti-CDK2 Antibody Application Details Handling References for anti-CDK2 antibody (ABIN359658) Images back to top
Antigen
Alternative Name CDK2 (CDK2 Antibody Abstract)
Background CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase
Gene ID 1017, 9606
UniProt P24941
Research Area Cell Cycle, CD Antigens, Surface Receptors of Immune Cells
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA

Application Details

Product Details anti-CDK2 Antibody Target Details CDK2 Handling References for anti-CDK2 antibody (ABIN359658) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CDK2 Antibody Target Details CDK2 Application Details References for anti-CDK2 antibody (ABIN359658) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-CDK2 antibody (ABIN359658)

Product Details anti-CDK2 Antibody Target Details CDK2 Application Details Handling Images back to top
Background publications

Moshinsky, Bellamacina, Boisvert, Huang, Hui, Jancarik, Kim, Rice: "SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2." in: Biochemical and biophysical research communications, Vol. 310, Issue 3, pp. 1026-31, 2003

Chow, Siu, Ho, Ma, Ho, Poon: "Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints." in: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 40815-28, 2003

Images

Product Details anti-CDK2 Antibody Target Details CDK2 Application Details Handling References for anti-CDK2 antibody (ABIN359658) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cyclin-Dependent Kinase 2 (CDK2) (C-Term) antibody (ABIN359658) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Cyclin-Dependent Kinase 2 (CDK2) (C-Term) antibody (ABIN359658) Western blot analysis of anti-CDK2 Antibody (C-term) in Jurkat cell line lysates (35u...