Browse our anti-CHUK (CHUK) Antibodies

Full name:
anti-conserved Helix-Loop-Helix Ubiquitous Kinase Antibodies (CHUK)
On www.antibodies-online.com are 364 conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Antibodies from 35 different suppliers available. Additionally we are shipping CHUK Kits (10) and CHUK Proteins (6) and many more products for this protein. A total of 394 CHUK products are currently listed.
Synonyms:
AI256658, CHUK, Chuk1, Fbx24, Fbxo24, IKBKA, ikk, IKK-alpha, IKK1, Ikka, ikkalpha, NFKBIKA, TCF16, zgc:56539
list all antibodies Gene Name GeneID UniProt
CHUK 1147 O15111
CHUK 12675  
CHUK 309361  

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All available anti-CHUK Antibodies

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Top referenced anti-CHUK Antibodies

  1. Human Monoclonal CHUK Primary Antibody for ChIP, FACS - ABIN252647 : Manna, Mukhopadhyay, Aggarwal: IFN-alpha suppresses activation of nuclear transcription factors NF-kappa B and activator protein 1 and potentiates TNF-induced apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 71 references for 252647

  2. Human Polyclonal CHUK Primary Antibody for WB - ABIN1881204 : Lahtela, Nousiainen, Stefanovic, Tallila, Viskari, Karikoski, Gentile, Saloranta, Varilo, Salonen, Kestilä: Mutant CHUK and severe fetal encasement malformation. in The New England journal of medicine 2010 (PubMed)
    Show all 5 references for 1881204

  3. Human Polyclonal CHUK Primary Antibody for WB - ABIN1881203 : Gouin, Adib-Conquy, Balestrino, Nahori, Villiers, Colland, Dramsi, Dussurget, Cossart: The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I{kappa}B kinase subunit IKK{alpha}. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 5 references for 1881203

  4. Human Monoclonal CHUK Primary Antibody for IP, WB - ABIN967550 : DiDonato, Hayakawa, Rothwarf, Zandi, Karin: A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. in Nature 1997 (PubMed)
    Show all 5 references for 967550

  5. Human Monoclonal CHUK Primary Antibody for IF, WB - ABIN393762 : Li, Morgan, Choksi, Zhang, Kim, Liu: MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. in Nature immunology 2010 (PubMed)
    Show all 5 references for 393762

  6. Human Polyclonal CHUK Primary Antibody for IHC, ELISA - ABIN1531285 : Régnier, Song, Gao, Goeddel, Cao, Rothe: Identification and characterization of an IkappaB kinase. in Cell 1997 (PubMed)
    Show all 3 references for 1531285

  7. Human Polyclonal CHUK Primary Antibody for ELISA, ICC - ABIN4324237 : Van Gammeren, Damrauer, Jackman, Kandarian: The IkappaB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)
    Show all 2 references for 4324237

  8. Human Polyclonal CHUK Primary Antibody for IHC (p), WB - ABIN196836 : Yuan, Feldman, Sun, Olashaw, Coppola, Sussman, Shelley, Nicosia, Cheng: Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for 196836

  9. Human Polyclonal CHUK Primary Antibody for IHC (p), WB - ABIN197306 : Ozes, Mayo, Gustin, Pfeffer, Pfeffer, Donner: NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. in Nature 1999 (PubMed)
    Show all 2 references for 197306

  10. Human Polyclonal CHUK Primary Antibody for IF (p), IHC (p) - ABIN681508 : Huang, Yang, Wang, Ma, Cui, Huang, Sheng, Weng, Xu: Immunostimulatory activity of protein hydrolysate from oviductus ranae on macrophage in vitro. in Evidence-based complementary and alternative medicine : eCAM 2015 (PubMed)
    Show all 2 references for 681508

More Antibodies against CHUK Interaction Partners

Human conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) interaction partners

  1. IKKalpha promotes migration through dynamic interactions with the EGF (show EGF Antibodies) promoter depending on the redox state within cells.

  2. the dual regulation of STAT1 (show STAT1 Antibodies) by IKKalpha in antiviral signaling suggests a role for IKKalpha in the fine-tuning of antiviral signaling in response to non-self RNA.

  3. In epithelial ovarian cancer cells, miR (show MLXIP Antibodies)-23a enhances the expression of IKKalpha. The proliferation, migration, and invasion of EOC cells are increased by IKKalpha.

  4. TLR signaling led to lower expression of LRRC14 (show LRRC14 Antibodies).

  5. IKKalpha is an important determinant of poor outcome in patients with ER-positive invasive ductal breast cancer and thus may represent a potential therapeutic target

  6. The molecular mechanisms involved in IKKalpha-related tumors. [review]

  7. this study shows that miR (show MLXIP Antibodies)-23a regulated IL-17 (show IL17A Antibodies)-mediated proinflammatory mediators expression in rheumatoid arthritis by directly targeting IKKalpha

  8. W346 effectively inhibited tumor necrosis factor (TNF-a (show TNF Antibodies))-induced NF-kappaB (show NFKB1 Antibodies) activation by suppressing IKK phosphorylation, inhibiting IkB (show NFKBIB Antibodies)-a degradation, and restraining the accumulation of NF-kappaB (show NFKB1 Antibodies) subunit p65 (show GORASP1 Antibodies) nuclear translocation. W346 also affected NF-kappaB (show NFKB1 Antibodies)-regulated downstream products involved in cycle arrest and apoptosis.

  9. Data indicate a significantly higher quantity of mesenchymal stromal cells (MSCs)was produced from human embryonic stem cells (hESCs) with IkappaB kinase (IKK)/nuclear factor kappa B (NF-kappaB (show NFKB1 Antibodies)) suppression.

  10. Findings indicate that IkappaB kinase inhibitor ACHP (show LMBR1 Antibodies) can slowdown the accumulation of collagen type I (COL1A1 (show COL1A1 Antibodies)).

Mouse (Murine) conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) interaction partners

  1. IKKalpha as a central mediator sensing both cytokine and microbial stimulation to suppress endoplasmic reticulum stress, thereby assuring antiinflammatory function during acute intestinal inflammation.

  2. The kinase IKKalpha inhibits activation of the transcription factor NF-kappaB (show NFKB1 Antibodies) by phosphorylating the regulatory molecule TAX1BP1 (show TAX1BP1 Antibodies).

  3. Data indicate that the inflammation and proliferation-related functions of I kappa B kinase (IKKbeta (show IKBKB Antibodies)) can be uncoupled by quinoxaline urea analog 13-197.

  4. Hematopoietic IKKalpha deficiency in mouse suppresses Akt (show AKT1 Antibodies) signaling, compromising monocyte/macrophage survival and this decreases early atherosclerosis.

  5. Anatomy of a negative feedback loop: the case of IkappaBalpha (show NFKBIA Antibodies).

  6. Epithelial-intrinsic IKK-alpha expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.

  7. IKKalpha mediated the repair of the kidney via infiltrated regulatory T (Treg) cells, which can produce anti-inflammatory cytokine IL10 (show IL10 Antibodies)

  8. phosphorylation of DBC1 (show DBC1 Antibodies) at its C terminus by IKKalpha facilitates its interaction with RelB (show RELB Antibodies) and IKKalpha, indicating that DBC1 (show DBC1 Antibodies)-mediated suppression of alternative NF-kappaB (show NFKB1 Antibodies) is regulated by IKKalpha.

  9. IKKalpha controls the inflammasome at the level of the adaptor molecule ASC (show STS Antibodies), which interacts with IKKalpha in the nucleus of resting macrophages in an IKKalpha kinase-dependent manner.

  10. Stimulated BTK (show BTK Antibodies)-deficient dendritic cells are defective in the induction of IKK alpha/beta phosphorylation and IRF-1 (show IRF1 Antibodies) activation.

Zebrafish conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) interaction partners

  1. These findings reveal a molecular mechanism regulating migration and invasion of epithelial cells and establish a key direct link between IKKbeta (show IKBKB Antibodies) and cell motility controlled by Rap (show LRPAP1 Antibodies)-integrin signaling.

  2. poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis

  3. Ikk1 negatively regulates NF-kappaB (show NFKB1 Antibodies) by sequestering NEMO (show IKBKG Antibodies) from active IKK complexes, indicating that IKK1 can function as a repressor of NF-kappaB (show NFKB1 Antibodies).

CHUK Antigen Profile

Antigen Summary

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Alternative names and synonyms associated with CHUK

  • conserved helix-loop-helix ubiquitous kinase (chuk) antibody
  • conserved helix-loop-helix ubiquitous kinase (CHUK) antibody
  • conserved helix-loop-helix ubiquitous kinase (Chuk) antibody
  • AI256658 antibody
  • CHUK antibody
  • Chuk1 antibody
  • Fbx24 antibody
  • Fbxo24 antibody
  • IKBKA antibody
  • ikk antibody
  • IKK-alpha antibody
  • IKK1 antibody
  • Ikka antibody
  • ikkalpha antibody
  • NFKBIKA antibody
  • TCF16 antibody
  • zgc:56539 antibody

Protein level used designations for CHUK

IKK-A , IKK-alpha , NFKBIKA , i kappa-B kinase alpha , ikBKA , inhibitor of nuclear factor kappa-B kinase subunit alpha , nuclear factor NF-kappa-B inhibitor kinase alpha , SPFH domain-containing protein 1 , conserved helix-loop-helix ubiquitous kinase , I-kappa-B kinase 1 , I-kappa-B kinase-alpha , IKK-a kinase , IkB kinase alpha subunit , Nuclear factor NFkappaB inhibitor kinase alpha , TCF-16 , transcription factor 16 , I kappa B kinase 1 , I-kappa-B kinase alpha , IKK alpha , IkappaB kinase alpha , ikappaB kinase , IkB kinase-a , IKK1 , IKKa , pky

GENE ID SPECIES
444556 Xenopus laevis
450673 Pan troglodytes
477796 Canis lupus familiaris
709511 Macaca mulatta
100174735 Pongo abelii
1147 Homo sapiens
12675 Mus musculus
309361 Rattus norvegicus
423669 Gallus gallus
100135662 Sus scrofa
281073 Bos taurus
393287 Danio rerio
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