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anti-Human Cyclin D1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • AI327039
  • bcl-1
  • bcl1
  • BCL1
  • cb161
  • ccnd1
  • CCND1
  • ccnd1a
  • ccnd1b
  • ccndbp1
  • cD1
  • cycd1
  • CycD1
  • Cyl-1
  • d11s287e
  • D11S287E
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • prad1
  • PRAD1
  • u21b31
  • U21B31
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • ZHM
Epitope
AA 70-120
79
25
19
14
12
12
10
10
9
9
8
6
6
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Goat, Human, Mouse (Murine), Rat (Rattus)
447
181
172
46
16
13
12
11
9
8
4
3
2
2
2
1
1
1
1
Host
Rabbit
310
188
1
Clonality
Polyclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
22
19
9
9
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
400
191
139
108
107
104
103
73
71
11
8
7
6
3
3
2
2
2
1
1
1
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Catalog No. ABIN671016
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088330376 ABIN892917 IF (p) Alexa Fluor 555 Rabbit IgG AA 70-120 Log in to see Polyclonal 1
0.00088330376 ABIN892918 IF (p) Alexa Fluor 350 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN892920 IF (p) Alexa Fluor 647 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN892919 IF (p) Alexa Fluor 488 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN671022 IF (p) Cy7 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN671021 IF (p) Cy5.5 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN671023 IF (p) FITC Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN671019 IF (p) Cy3 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN671020 IF (p) Cy5 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN2809057 IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 70-120 Log in to see Polyclonal
0.00088330376 ABIN684478 IF (p) IHC (p) WB Rabbit IgG pThr286 Log in to see Polyclonal

Top referenced anti-Cyclin D1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-Cyclin D1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Goat
Western Blotting (WB) 373 Antibodies 156 Antibodies 147 Antibodies 3 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Staining (ICS) 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 108 Antibodies 66 Antibodies 66 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 140 Antibodies 66 Antibodies 64 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 95 Antibodies 47 Antibodies 47 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 66 Antibodies

General

Antigen Cyclin D1 (CCND1) Antibodies
Epitope AA 70-120
(79), (25), (19), (14), (12), (12), (10), (10), (9), (9), (8), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Goat, Human, Mouse (Murine), Rat (Rattus)
(447), (181), (172), (46), (16), (13), (12), (11), (9), (8), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(310), (188), (1)
Clonality
Polyclonal
Conjugate This Cyclin D1 antibody is un-conjugated
(22), (19), (9), (9), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(400), (191), (139), (108), (107), (104), (103), (73), (71), (11), (8), (7), (6), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 12 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 Antibody (ABIN671016) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse Cyclin D1
Isotype IgG

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling References for anti-Cyclin D1 Antibody (ABIN671016) Images back to top
Antigen
Alternative Name Cyclin D1 (CCND1 Antibody Abstract)
Background

Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner (By similarity).

Subcellular location: Cytoplasm, Nucleus


Synonyms: cD1, CycD1, Cyl-1, PRAD1, bcl-1, AI32739, G1/S-specific cyclin-D1, Ccnd1
Gene ID 12443
UniProt P25322
Research Area Cancer, Cell Cycle
Pathways PI3K-Akt Signaling, Cell Division Cycle

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling References for anti-Cyclin D1 Antibody (ABIN671016) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details References for anti-Cyclin D1 Antibody (ABIN671016) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-Cyclin D1 Antibody (ABIN671016)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Product cited in:

Zhang, Pan, Xu, Niu, Ma, Xu: "Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells." in: Gene, Vol. 563, Issue 1, pp. 45-51, 2015

Wang, Yang, Liu, Huang, Wang, Chen, Chen: "RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53-Fbxw7 pathway." in: Biochemical and biophysical research communications, Vol. 454, Issue 1, pp. 71-7, 2015

Yang, Wang, Hui, Li, Jiang: "SOX 1, contrary to SOX 2, suppresses proliferation, migration, and invasion in human laryngeal squamous cell carcinoma by inhibiting the Wnt/β-catenin pathway." in: Tumour biology, 2015

Shi, Lu, Zhou, Tan, He, Ding, Tian, Wang, Wang: "Long non-coding RNA Loc554202 regulates proliferation and migration in breast cancer cells." in: Biochemical and biophysical research communications, Vol. 446, Issue 2, pp. 448-53, 2014

Ye, Li, Li, Yang, Niu, Wang: "Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo." in: Journal of ethnopharmacology, Vol. 153, Issue 1, pp. 258-67, 2014

Lin, Wang, Wang, Fang, Zhang, Yang, Guo, Lin, Zhang, Wang: "Lithocarpus polystachyus REHD leaf aqueous extract inhibits human breast cancer growth in vitro and in vivo." in: Nutrition and cancer, Vol. 66, Issue 4, pp. 613-24, 2014

He, Xiang, Zong, Yan, Yu, Liu, Zou, Yang: "CDK2-AP1 inhibits growth of breast cancer cells by regulating cell cycle and increasing docetaxel sensitivity in vivo and in vitro." in: Cancer cell international, Vol. 14, Issue 1, pp. 130, 2014

Li, Yu, Liu, Zhu, He, Peng, Hua: "miR-34c works downstream of p53 leading to dairy goat male germline stem-cell (mGSCs) apoptosis." in: Cell proliferation, Vol. 46, Issue 2, pp. 223-31, 2013 (1:1000).

Teng, Chang, Wang, Lu, Wu, Yang, Chiu, Yang, Hsu, Ho: "Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer." in: Biomaterials, Vol. 34, Issue 30, pp. 7462-70, 2013

Wang, Wu, Gao, Chen, Gu, Ding, Guo: "Elevated toll-like receptor 3 inhibits pancreatic ?-cell proliferation through G1 phase cell cycle arrest." in: Molecular and cellular endocrinology, Vol. 377, Issue 1-2, pp. 112-22, 2013

Zhang, Tan, Wang, Chen, Quan, Xian, Zhang, He, Zhang: "Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway." in: Experimental cell research, Vol. 320, Issue 1, pp. 119-27, 2013

Chen, Shi, Liu, Fang, Zhang, Zhao: "Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis." in: BMC cancer, Vol. 12, pp. 464, 2012 (1:1000).

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 Antibody (ABIN671016) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Cyclin D...
Immunohistochemistry (IHC) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Cyclin D...
Western Blotting (WB) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) A549 cells probed with Anti-Cyclin D1 Polyclonal Antibody at 1:5000 90min in 37˚C.