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anti-Human Cyclin D1 antibody for Immunohistochemistry

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • ccnd1b
  • prad1
  • bcl1
  • d11s287e
  • u21b31
  • ccndbp1
  • ccnd1
  • ZHM
  • CCND1
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • ccnd1a
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • cyclin D1
  • Cyclin-D1-binding protein 1 homolog
  • cyclin Dx
  • zgc:162082
  • G1/S-specific cyclin-D1
  • ccnd1-b
  • ccnd1
  • ccndbp1
  • ccndx
  • zgc:162082
  • CCND1
  • Ccnd1
  • ccnd1-a
Epitope
N-Term
77
22
21
14
13
12
10
10
9
9
8
7
6
5
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Xenopus laevis
465
186
175
44
19
15
14
12
10
8
5
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
315
194
19
4
Clonality
Polyclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
23
20
12
10
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
403
207
123
110
108
103
99
80
53
12
11
8
8
7
6
4
3
2
2
2
1
1
Options
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Catalog No. ABIN2777893
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.22987 ABIN1532284 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
8.22987 ABIN2704689 IHC WB Rabbit C-Term, pSer286 Log in to see Polyclonal
8.22987 ABIN2471067 ICC FACS IP IHC ELISA WB Mouse IgG1 Log in to see CD1-1
8.22987 ABIN1871539 IHC WB Rabbit IgG Log in to see Polyclonal
8.22987 ABIN3026634 FACS IF IHC WB Mouse IgG2a, kappa Log in to see DCS-6
8.22987 ABIN408117 IHC (p) IHC WB Rabbit Log in to see Polyclonal
8.22987 ABIN2163363 IHC ELISA WB Rabbit IgG Thr286 Log in to see Polyclonal
8.22987 ABIN3030588 IF IHC ELISA WB Rabbit Ig Fraction AA 68-97 Log in to see Polyclonal
8.22987 ABIN2404174 IHC WB Rabbit IgG Log in to see Polyclonal
8.22987 ABIN2428015 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
8.22987 ABIN3024574 FACS IF IHC WB Mouse IgG2a, kappa Log in to see SPM587
8.22987 ABIN2425743 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN967430 FACS IP IHC WB Mouse IgG1 full length Log in to see G124-326 5
1 ABIN967431 FACS IP IHC WB Mouse IgG1 full length Log in to see G124-326 5
1 ABIN3182196 ELISA IHC WB Rabbit IgG pThr286 Log in to see Polyclonal
1 ABIN3184144 ELISA IHC WB Rabbit IgG Ser166 Log in to see Polyclonal
1 ABIN790994 IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN199058 FACS IF IHC WB FITC Mouse IgG2a, kappa Log in to see
1 ABIN1821008 IHC Rabbit IgG C-Term Log in to see SP4
1 ABIN1824294 IHC WB Mouse IgG2a Log in to see 5D4

Top referenced anti-Cyclin D1 antibody for Immunohistochemistry

Similar anti-Cyclin D1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Rabbit Cow (Bovine) Chicken Xenopus laevis
Cytometry by Time of Flight (CyTOF) 4 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 356 Antibodies 11 Antibodies 138 Antibodies 2 Antibodies 130 Antibodies 11 Antibodies 10 Antibodies 4 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Staining (ICS) 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 1 Antibodies 94 Antibodies 49 Antibodies

General

Antigen Cyclin D1 (CCND1) Antibodies
Epitope N-Term
(77), (22), (21), (14), (13), (12), (10), (10), (9), (9), (8), (7), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Xenopus laevis
(465), (186), (175), (44), (19), (15), (14), (12), (10), (8), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(315), (194), (19), (4)
Clonality
Polyclonal
Conjugate This Cyclin D1 antibody is un-conjugated
(23), (20), (12), (10), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(403), (207), (123), (110), (108), (103), (99), (80), (53), (12), (11), (8), (8), (7), (6), (4), (3), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 Antibody (ABIN2777893) Images
Blocking Peptide Blocking peptide for this product available: ABIN974600
Sequence KCEEEVFPLA MNYLDRFLSL EPVKKSRLQL LGATCMFVAS KMKETIPLTA
Predicted Reactivity Bovine : 100 %, Human : 100 %, Pig : 100 %, Dog : 90 %, Guinea pig : 90 %, Mouse : 90 %, Rabbit : 90 %, Rat : 90 %, Chicken : 80 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against CCND1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CCND1

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling References for anti-Cyclin D1 Antibody (ABIN2777893) Images back to top
Antigen
Alternative Name CCND1 (CCND1 Antibody Abstract)
Background CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
Molecular Weight 34 kDa
Gene ID 595
NCBI Accession NM_053056, NP_444284
UniProt P24385
Pathways PI3K-Akt Signaling, Cell Division Cycle

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling References for anti-Cyclin D1 Antibody (ABIN2777893) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 295 AA

Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details References for anti-Cyclin D1 Antibody (ABIN2777893) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Cyclin D1 Antibody (ABIN2777893)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Background publications

Kibel, Jin, Klim, Luly, A Roehl, Wu, Suarez: "Association between polymorphisms in cell cycle genes and advanced prostate carcinoma." in: The Prostate, Vol. 68, Issue 11, pp. 1179-86, 2008

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 Antibody (ABIN2777893) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 antibody (CCND1) (N-Term) (ABIN2777893) anti-Cyclin D1 (CCND1) (N-Term) antibody