anti-Mouse (Murine) Cyclin D1 antibody for Immunohistochemistry (Formalin-fixed Sections)

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • ccnd1b
  • prad1
  • bcl1
  • d11s287e
  • u21b31
  • ccndbp1
  • ccnd1
  • ZHM
  • CCND1
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • ccnd1a
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • cyclin D1
  • Cyclin-D1-binding protein 1 homolog
  • cyclin Dx
  • zgc:162082
  • G1/S-specific cyclin-D1
  • ccnd1-b
  • ccnd1
  • ccndbp1
  • ccndx
  • zgc:162082
  • CCND1
  • Ccnd1
  • ccnd1-a
Epitope
full length
79
24
21
16
14
12
11
10
9
8
8
6
6
5
5
5
5
5
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
488
243
236
44
21
20
19
16
16
14
5
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
326
203
19
4
Clonality
Monoclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
26
23
15
10
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Intracellular Staining (ICS), Immunoprecipitation (IP), Western Blotting (WB)
447
209
133
127
117
109
108
80
50
14
13
12
8
8
7
5
5
3
1
1
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Catalog No. ABIN967539
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4888511 FACS Func ICC IHC (f) IHC (p) IP WB Mouse IgG2a AA 1-295 Log in to see DCS-6
1 ABIN4888512 FACS Func ICC IHC (f) IHC (p) IP WB PE Mouse IgG2a AA 1-295 Log in to see DCS-6

General

Antigen Cyclin D1 (CCND1) Antibodies
Epitope full length
(79), (24), (21), (16), (14), (12), (11), (10), (9), (8), (8), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(488), (243), (236), (44), (21), (20), (19), (16), (16), (14), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(326), (203), (19), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cyclin D1 antibody is un-conjugated
(26), (23), (15), (10), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Intracellular Staining (ICS), Immunoprecipitation (IP), Western Blotting (WB)
(447), (209), (133), (127), (117), (109), (108), (80), (50), (14), (13), (12), (8), (8), (7), (5), (5), (3), (1), (1)
Pubmed 4 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN967539) Images
Brand BD Pharmingen™
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Please refer to us for technical protocols.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Full-length Cyclin D1 Recombinant Protein
Clone DCS-6
Isotype IgG2a

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN967539) Images back to top
Antigen
Alternative Name Cyclin D1 (CCND1 Antibody Abstract)
Background Cyclins and cyclin-dependent kinases (Cdks) have been shown to be subunits of cell cycle dependent protein kinases that regulate key events during the progression of the cell cycle and are evolutionarily highly conserved. Specific substrates for Cdk/cyclin kinases include nuclear lamins, histones, oncogenes (c-src, c-abl, SV40 large-T), tumor suppressor genes (the retinoblastoma protein [Rb] and p53), nucleolin, RNA polymerase II and others. D-type cyclins are involved in regulating the passage of mammalian cells through G1. In SDS-PAGE, D-type cyclins migrate at the following molecular weights: cyclin D1 (36 kDa), cyclin D2 (35 kDa), and cyclin D3 [31 and 34 kDa (doublet)]. Rodent cyclin D1 homologues (Cyl1) have been reported to typically migrate as a 36 kDa doublet. The mouse anti-human cyclin D1 antibody (clone DCS-6) recognizes human cyclin D1 (36 kDa) and has been reported to crossreact with rat and mouse cyclin D1 homologues (Cyl1). It does not crossreact with human cyclins D2 and D3.
Molecular Weight 36 kDa
Research Area Cancer, Cell Cycle
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN967539) Images back to top
Comment

Related Products: ABIN968585, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details ProductDetails: References for anti-Cyclin D1 antibody (ABIN967539) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

ProductDetails: References for anti-Cyclin D1 antibody (ABIN967539)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Product cited in:

Darzynkiewicz, Gong, Juan, Ardelt, Traganos: "Cytometry of cyclin proteins." in: Cytometry, Vol. 25, Issue 1, pp. 1-13, 1997

de Boer, Schuuring, Dreef, Peters, Bartek, Kluin, van Krieken: "Cyclin D1 protein analysis in the diagnosis of mantle cell lymphoma." in: Blood, Vol. 86, Issue 7, pp. 2715-23, 1995

Lukas, Pagano, Staskova, Draetta, Bartek: "Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines." in: Oncogene, Vol. 9, Issue 3, pp. 707-18, 1994

Meyerson, Harlow: "Identification of G1 kinase activity for cdk6, a novel cyclin D partner." in: Molecular and cellular biology, Vol. 14, Issue 3, pp. 2077-86, 1994

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN967539) back to top
Supplier Images
Western Blotting (WB) image for anti-Cyclin D1 (CCND1) (full length) antibody (ABIN967539) Western blot analysis of Cyclin D1. MCF7 cell lysates (Human breast adenocarcinoma, A...
 image for anti-Cyclin D1 (CCND1) (full length) antibody (ABIN967539) anti-Cyclin D1 (CCND1) (full length) antibody (Image 2)
Western Blotting (WB) image for anti-Cyclin D1 (CCND1) (full length) antibody (ABIN967539) anti-Cyclin D1 (CCND1) (full length) antibody (Image 3)