Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Human Cyclin D1 ELISA Kit for Sandwich ELISA - ABIN414406
Bocci, Fioravanti, La Motta, Orlandi, Canu, Di Desidero, Mugnaini, Sartini, Cosconati, Frati, Antonelli, Berti, Miccoli, Da Settimo, Danesi: Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells. in Biochemical pharmacology 2011
Show all 5 Pubmed References
Results suggest that the TCF (show HNF4A ELISA Kits)/LEF signaling pathway participates in the regulation of cyclin D1 induction during the generation of the dorsal nervous system in early frog embryogenesis.
while cyclin B1 RNA granules were disassembled in a manner dependent on actin filament depolymerization, certain fractions of mos RNA granules were disassembled independently of actin filaments. These results suggest that cytoplasmic regulation of translationally repressed mRNAs by formation of different RNA granules is a key mechanism for translational control of
Maid (show CCNDBP1 ELISA Kits) is important regulator of hepatocarcinogenesis and aging
show that the knockdown of smc1a (show SMC1A ELISA Kits) in zebrafish impairs neural development, increases apoptosis, and specifically down-regulates Ccnd1 levels
Reduction of cyclin D1 expression compromises zebrafish eye and head development.
Role in cell cycle control is mediated by meis1 (show MEIS1 ELISA Kits) regulating cyclin D1 and c-myc (show MYC ELISA Kits) transcription in the embryonic eye.
results showed that fascaplysin inhibited ovarian cancer cell proliferation, invasion and migration, as well as inducing S arrest and cell apoptosis. Treatment with fascaplysin also suppressed CDK4 (show CDK4 ELISA Kits), cyclin D1, Bcl-2 (show BCL2 ELISA Kits), and VEGFA (show VEGFA ELISA Kits) expression at protein levels
Mutation in the CCND1 gene is associated with acute myeloid leukemia (show BCL11A ELISA Kits).
The first preclinical study evaluates the response to CDK4/6 (show CDK4 ELISA Kits) inhibition in endometrial malignancies driven by PTEN deficiency, and it reveals an important role of cyclin D-CDK4/6 (show CDK4 ELISA Kits) activity in their development.
High CCND1 expression is associated with oropharyngeal squamous cell carcinoma.
Describe a regulatory loop miR (show MLXIP ELISA Kits)-218-CDK6 (show CDK6 ELISA Kits)/CyclinD1-E2F1 (show E2F1 ELISA Kits) whose disruption may contribute to cell cycle progression in gastric cancer.
EGF induces hair follicle-derived mesenchymal stem cell proliferation through the EGFR/ERK and AKT pathways, but not through STAT-3. The G1/S transition was stimulated by upregulation of cyclinD1 and inhibition of p16 expression.
Case Report: in the absence of the typical CCND1/IGH@ fusion, t(11;12)(q13;p11.2) promotes Mantle cell lymphoma pathogenesis by eliminating miRNA interaction elements within the 3'-UTR (show UTS2R ELISA Kits) of the CCND1 mRNA transcript consequently resulting in CCND1 overexpression.
The CCND1 genes were found very close to the IGH locus in naive B cells and further away after maturation. In contrast, the CMYC alleles became localized closer to an IGH locus at the stage of SHM/CSR.
Consistently, samples from oral squamous cell carcinoma (OSCC) patients exhibited a noticeably stronger CREPT expression than noncancerous samples. In contrast, knocking down of CREPT in OSCC cell lines significantly reduced proliferation, colony formation and migration as well as the expression of cyclin D1 and c-Myc (show MYC ELISA Kits), but promoted apoptosis.
Histone H2A T120 phosphorylation promotes oncogenic transformation via upregulation of cyclin D1.
NMB or NMBR (show NMBR ELISA Kits) silencing inhibited M-CSF (show CSF1R ELISA Kits)/c-Fms (show CSF1R ELISA Kits)-mediated downstream signaling pathways like activation of ERK (show EPHB2 ELISA Kits) and Akt (show AKT1 ELISA Kits) and induction of D-type cyclins, cyclin D1 and D2.
our results are consistent with an epithelial proliferative growth mechanism linking CTNNB1 (show CTNNB1 ELISA Kits)-driven Ccnd1 transcription and estrogen-mediated CCND1 protein stabilization.
identify Pax5 (show PAX5 ELISA Kits) and cyclin D1 as Zfp521 target genes, and suggest that excessive B-cell proliferation observed in mice with retroviral insertions near the Zfp521 gene is due to an up-regulation of cyclin D1 in B-cells.
Data show that expression of the Oct-4 (show POU5F1 ELISA Kits), Sox2 (show SOX2 ELISA Kits), Klf4 (show KLF4 ELISA Kits), and c-Myc (show MYC ELISA Kits) (OSKM) reprogramming factors induces Cyclin D1 expression, and the increased Cyclin D1 expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.
study shows that PLCgamma1 (show PLCG1 ELISA Kits) controls osteoclast numbers via a CSF-1 (show CSF1 ELISA Kits)-dependent DAG/beta-catenin (show CTNNB1 ELISA Kits)/cyclinD1 pathway.
Regarding extratelomeric activities, our results showed a decrease of 64, 38 and 25% in the transcription of c-Myc (show MYC ELISA Kits), Cyc (show CYCS ELISA Kits)-D1 and TERT (show TERT ELISA Kits), respectively (p<0.05) after AZT treatment. Furthermore, we found an effect on cell migration, reaching an inhibition of 48% (p<0.05) and a significant passage-dependent increase on cell doubling time during treatment.
Using Ccnd1 knockout mice, the study shows that Ccnd1 expression significantly contributes to tumor incidence in teratoma (show DND1 ELISA Kits) susceptible mice without being necessary for normal germ cell or testis development.
Ras (G12V)-induced cyclin D1 protein synthesis was markedly suppressed by the knockdown of IL-33 (show IL33 ELISA Kits).
Novel RNA-binding activity of MYF5 (show MYF5 ELISA Kits) enhances Ccnd1 mRNA translation during myogenesis.
cyclin D1, CDK2 (show CDK2 ELISA Kits) and CDK4 (show CDK4 ELISA Kits) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation
17beta-estradiol (E2) induces cell proliferation of bovine arterial endothelial cells through upregulation of cyclin D1 via non-genomic activation of the extracellular signal-regulated microtubule-associated Protein 2 kinase (ERK1 (show MAPK3 ELISA Kits) kinase) pathway.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
G1/S-specific cyclin-D1 b
, cyclin D1 b
, parathyroid adenomatosis 1
, cyclin D1 (PRAD1: parathyroid adenomatosis 1)
, Cyclin-D1-binding protein 1 homolog
, cyclin Dx
, cyclin-D1-binding protein 1 homolog
, zebrafish homolog of Maid
, cyclin D1
, G1/S-specific cyclin-D1
, B-cell CLL/lymphoma 1
, B-cell lymphoma 1 protein
, BCL-1 oncogene
, PRAD1 oncogene
, G1/S-specific cyclin-D1 a
, cyclin D1 a (PRAD1: parathyroid adenomatosis 1)