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Browse our anti-FOXO1 (FOXO1) Antibodies

Full name:
anti-Forkhead Box O1 Antibodies (FOXO1)
On are 422 Forkhead Box O1 (FOXO1) Antibodies from 35 different suppliers available. Additionally we are shipping FOXO1 Kits (55) and FOXO1 Proteins (9) and many more products for this protein. A total of 507 FOXO1 products are currently listed.
Afxh, AI876417, FKH1, Fkhr, Fkhr1, foxo1, FoxO1A, FoxO1a.1, xFoxO1, zgc:153388
list all antibodies Gene Name GeneID UniProt
FOXO1 2308 Q12778
FOXO1 56458 Q9R1E0
FOXO1 84482  

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Most Popular Reactivities for anti-FOXO1 (FOXO1) Antibodies

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anti-Human FOXO1 Antibodies:

anti-Mouse (Murine) FOXO1 Antibodies:

anti-Rat (Rattus) FOXO1 Antibodies:

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Top referenced anti-FOXO1 Antibodies

  1. Human Polyclonal FOXO1 Primary Antibody for IF, IHC (p) - ABIN197334 : Gan, Zheng, Chabot, Unterman, Quirion: Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors. in Journal of neurochemistry 2005 (PubMed)
    Show all 5 references for ABIN197334

  2. Human Polyclonal FOXO1 Primary Antibody for IHC (p), WB - ABIN390584 : Jung, Lee, Kim, Jung, Seo, Kim, Cho, Lee, Park, Lee: Forkhead transcription factor FoxO1 inhibits insulin- and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 2 references for ABIN390584

  3. Human Monoclonal FOXO1 Primary Antibody for WB - ABIN614182 : Huusko, Ponciano-Jackson, Wolf, Kiefer, Azorsa, Tuzmen, Weaver, Robbins, Moses, Allinen, Hautaniemi, Chen, Elkahloun, Basik, Bova, Bubendorf, Lugli, Sauter, Schleutker, Ozcelik, Elowe, Pawson, Trent et al.: Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. ... in Nature genetics 2004 (PubMed)
    Show all 2 references for ABIN614182

  4. Human Polyclonal FOXO1 Primary Antibody for EIA, WB - ABIN453020 : Lau, Koty, Nalbantoglu: Differential response of glioma cells to FOXO1-directed therapy. in Cancer research 2009 (PubMed)
    Show all 2 references for ABIN453020

  5. Human Polyclonal FOXO1 Primary Antibody for EIA, WB - ABIN783624 : Anderson, Viars, Czekay, Cavenee, Arden: Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. in Genomics 1998 (PubMed)

  6. Human Polyclonal FOXO1 Primary Antibody for ELISA, WB - ABIN190814 : Paik, Kollipara, Chu, Ji, Xiao, Ding, Miao, Tothova, Horner, Carrasco, Jiang, Gilliland, Chin, Wong, Castrillon, DePinho: FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. in Cell 2007 (PubMed)

  7. Cow (Bovine) Polyclonal FOXO1 Primary Antibody for WB - ABIN2779460 : Amstutz, Wachtel, Troxler, Kleinert, Ebauer, Haneke, Oehler-Jänne, Fabbro, Niggli, Schäfer: Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities. in Cancer research 2008 (PubMed)

  8. Cow (Bovine) Polyclonal FOXO1 Primary Antibody for WB - ABIN2792531 : Okamoto, Hribal, Lin, Bennett, Ward, Accili: Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. in The Journal of clinical investigation 2006 (PubMed)

More Antibodies against FOXO1 Interaction Partners

Cow (Bovine) Forkhead Box O1 (FOXO1) interaction partners

  1. downregulation of SIRT1 (show SIRT1 Antibodies) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age

  2. FOXO (show FOXO3 Antibodies) is a key regulator of ROS (show ROS1 Antibodies)-induced apoptosis in mammalian cells.

  3. Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (show NCAM1 Antibodies)-1 mRNA.

  4. The results demonstrate pathways through which two different mediators, TNF-alpha (show TNF Antibodies) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.

Human Forkhead Box O1 (FOXO1) interaction partners

  1. The studies identify a P/CAF (show KAT2B Antibodies)-PAX3 (show PAX3 Antibodies)-FOXO1 signalling node that promotes oncogenesis and may contribute to MyoD (show MYOD1 Antibodies) dysfunction in Alveolar rhabdomyosarcoma (ARMS).

  2. Decidualization requires transcriptional upregulation of FOXO1. FOXO1 is transcribed from the same promoter in Decidual Stromal Cell as in endometrial stromal fibroblasts. Comparing the activities of FOXO1 promoters from human, mouse, manatee (Afrotheria), and opossum (marsupial) revealed that FOXO1 promoter evolved responsiveness to decidualization signals in the stem lineage of eutherians.

  3. In human fetal pancreatic progenitor cells, FoxO1 knockdown or FoxO1 inhibitor significantly upregulated Ngn3 (show NEUROG3 Antibodies) and insulin (show INS Antibodies) as well as the markers such as Glut2 (show SLC2A2 Antibodies), Kir6.2 (show KCNJ11 Antibodies), SUR1 (show ABCC8 Antibodies), and VDCC, which are designated for mature beta cells. Overexpression of FoxO1 suppressed the induction and reduced expression of these beta cell markers. these results suggest that FoxO1 may act as a repressor to inhibit cell differentiation in the...

  4. Our data suggested that miR (show MLXIP Antibodies)-101 suppressed HBV replication and expression partially by targeting FOXO1, providing new insights into the molecular mechanisms of miR (show MLXIP Antibodies)-101 in HBV-host interactions and a promising therapeutic target for HBV replication.

  5. The age-associated higher expression of miR (show MLXIP Antibodies)-96 and miR (show MLXIP Antibodies)-145 might contribute to the lower expression of IGF-1R (show IGF1R Antibodies) while the higher expression of miR (show MLXIP Antibodies)-96, miR (show MLXIP Antibodies)-145 and miR (show MLXIP Antibodies)-9 might contribute to the lower expression of FOXO1 in peripheral blood mononuclear cells of aging humans.

  6. Lysophosphatidic acid/PKD-1 (show PKD1 Antibodies) signaling leads to nuclear accumulation of histone deacetylase 7 (show HDAC7 Antibodies), where it interacts with forkhead box protein O1 to suppress endothelial CD36 (show CD36 Antibodies) transcription and mediates silencing of antiangiogenic switch, resulting in proangiogenic and proarteriogenic reprogramming.

  7. Report shows that silencing MARCH3 (show MARCH3 Antibodies) protects the endothelial barrier and upregulates OCLN (show OCLN Antibodies) in MARCH3 (show MARCH3 Antibodies)-depleted cells. MARCH3 (show MARCH3 Antibodies) silencing results in the strengthening of cell-cell contacts and inactivates FoxO1.

  8. The diabetic state is network-wide explained by attenuation of an mTORC1-to-insulin receptor substrate-1 (IRS1 (show IRS1 Antibodies)) feedback and reduced abundances of insulin receptor (show INSR Antibodies), GLUT4 (show SLC2A4 Antibodies), AS160 (show TBC1D4 Antibodies), ribosomal protein S6 (show RPS6 Antibodies), and FOXO1. The model demonstrates that attenuation of the mTORC1-to-IRS1 (show IRS1 Antibodies) feedback is a major mechanism of insulin (show INS Antibodies) resistance in the diabetic state.

  9. after AKT-mediated phosphorylation at serine 319, FOXO1 binds to IQGAP1, a hub for activation of the MAPK pathway, and impedes IQGAP1-dependent phosphorylation of ERK1/2 (pERK1/2).

  10. FOXO1 down-regulation and p53 (show TP53 Antibodies) overexpression characterizes a group of high-grade, pT1 (show ZNF77 Antibodies) stage bladder tumors with an increased probability of disease recurrence.

Pig (Porcine) Forkhead Box O1 (FOXO1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies)-FOXO1 signaling and suppressing the activation of TLR4 (show TLR4 Antibodies) and/or NOD2 (show NOD2 Antibodies) signaling pathways.

  2. let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (show MAP3K1 Antibodies) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.

  3. inhibition of FoxO1 expression level caused by miR (show MYLIP Antibodies)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (show MYLIP Antibodies)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1

  4. Results show that FoxO1 likely regulates MyHC I (show MYH7 Antibodies) negatively and MyHC IIx and MyHC IIb (show MYH4 Antibodies) positively and may play a pivotal role in the determination of muscle fiber type.

  5. Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (show TNFSF10 Antibodies) and Fas ligand FasL (show FASL Antibodies) expression during follicular atresia.

  6. Data show that IL-4 (show IL4 Antibodies) induces upregulation of the junction protein claudin-5 (show CLDN5 Antibodies) in endothelial cells (ECs) through activation of Jak (show JAK3 Antibodies)/STAT6 (show STAT6 Antibodies) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.

  7. FoxO1 and C/EBPb (show CEBPB Antibodies) regulate preadipocyte adipogenesis possibly through C/EBPb (show CEBPB Antibodies)-> FoxO1-> C/EBPb (show CEBPB Antibodies) feedback regulatory loop and FoxO1-C/EBPb (show CEBPB Antibodies) protein complex.

  8. FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.

  9. concluded that PI 3 (show PI3 Antibodies)-kinase and Akt (show AKT1 Antibodies) are activated after renal ischemia/reperfusion and that Akt (show AKT1 Antibodies) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (show FOXO3 Antibodies), which may affect epithelial cell fate in acute renal failure.

  10. FoxO1a can regulate p27kip nuclear localization

Mouse (Murine) Forkhead Box O1 (FOXO1) interaction partners

  1. Increased Forkhead box (show FOXO Antibodies) protein 1 (FoxO1) acetylation and nuclear retention was followed by progressive FoxO1 loss in beta cells that marked the onset of diabetes.

  2. Results show that microRNA miR (show MLXIP Antibodies)-181c attenuated nitration stress through regulating forkhead box O1 (FoxO1) expression and affecting endothelial cell function, suggesting a target for the development of preventive or therapeutic agents against diabetes mellitus (DM).

  3. Foxo1, Foxo3a (show FOXO3 Antibodies), and Foxo4 (show FOXO4 Antibodies) in chondrocytes regulate endochondral bone formation.

  4. Lysophosphatidic acid/PKD-1 (show PKD1 Antibodies) signaling leads to nuclear accumulation of histone deacetylase 7 (show HDAC7 Antibodies), where it interacts with forkhead box protein O1 to suppress endothelial CD36 (show CD36 Antibodies) transcription and mediates silencing of antiangiogenic switch, resulting in proangiogenic and proarteriogenic reprogramming.

  5. A role of FOXO1 in the regulatory T cell differentiation process.TGF-beta induces the phosphorylation of FOXO1 in CD4 (show CD4 Antibodies)+ T cells.

  6. Fucosterol inhibited adipogenesis of 3T3-L1 preadipocytes through modulation of FoxO (show FOXO3 Antibodies) signalling pathway.

  7. We verified a positive correlation between the level of mir (show MLXIP Antibodies)- 182 and symptom severity of experimental autoimmune encephalomyelitis (EAE) in mice and provide evidence that mir (show MLXIP Antibodies)-182 inhibited Treg cells specialization through Foxo1 dependent pathway, during the pathogenesis of EAE

  8. These findings suggest that specific overexpression of renal FoxO1 decreases podocyte apoptosis, which may be explained in part by its regulation of PINK1 (show PINK1 Antibodies), and that targeting FoxO1 may represent a novel therapeutic approach for diabetic nephropathy.

  9. However, Prep1 doesn't affect gluconeogenesis in the absence of insulin (show INS Antibodies). Also, we observed that nuclear content of gluconeogenic transcription factor FOXO1 was greatly reduced in Prep1 knockout hepatocytes. These findings suggest that Prep1 may control hepatic insulin (show INS Antibodies) sensitivity by targeting FOXO1 nuclear stability.

  10. These data suggest insulin (show INS Antibodies) acts on beta-cells in an endocrine manner in the normal situation; and that in beta-cells lacking insulin (show INS Antibodies) receptors, insulin (show INS Antibodies) and glucose minimally activate the Akt (show AKT1 Antibodies) pathway, while ERK (show EPHB2 Antibodies) phosphorylation and FoxO1 nuclear export occur independently of insulin (show INS Antibodies) signaling.

Xenopus laevis Forkhead Box O1 (FOXO1) interaction partners

  1. FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (show SOD1 Antibodies) and catalase (show CAT Antibodies) mRNA and protein levels in this organ.

Zebrafish Forkhead Box O1 (FOXO1) interaction partners

  1. These results indicate that miR (show MYLIP Antibodies)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.

  2. gas6 (show GAS6 Antibodies) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (show AKT1 Antibodies)-dependent inactivation of FOXO1a.

FOXO1 Antigen Profile

Antigen Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Alternative names and synonyms associated with FOXO1

  • forkhead box O1 (FOXO1) antibody
  • forkhead box O1 (foxo1) antibody
  • forkhead box O1 (Foxo1) antibody
  • forkhead box O1 a (foxo1a) antibody
  • Afxh antibody
  • AI876417 antibody
  • FKH1 antibody
  • Fkhr antibody
  • Fkhr1 antibody
  • foxo1 antibody
  • FoxO1A antibody
  • FoxO1a.1 antibody
  • xFoxO1 antibody
  • zgc:153388 antibody

Protein level used designations for anti-Forkhead Box O1 (FOXO1) Antibodies

forkhead box O1 , forkhead box O1A , forkhead box O1A (rhabdomyosarcoma) , forkhead box protein O1 , forkhead box protein O1-like , forkhead box protein O1A , forkhead, Drosophila, homolog of, in rhabdomyosarcoma , Forkhead box protein O1A , Forkhead in rhabdomyosarcoma , forkhead/winged helix transcription factor FOXO1a , forkhead in rhabdomyosarcoma , forkhead box O1a , forkhead protein 1 , xFoxO1 , forkhead box protein O1-A , fox family transcription factor FoxO1a.1 , foxhead box protein O1-A

100050481 Equus caballus
282234 Bos taurus
467352 Pan troglodytes
493378 Xenopus (Silurana) tropicalis
700030 Macaca mulatta
100460676 Pongo abelii
100594615 Nomascus leucogenys
2308 Homo sapiens
374231 Gallus gallus
397077 Sus scrofa
506618 Bos taurus
56458 Mus musculus
84482 Rattus norvegicus
444991 Xenopus laevis
477295 Canis lupus familiaris
101107877 Ovis aries
768121 Danio rerio
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