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|Antigen||Forkhead Box O1 (FOXO1) Antibodies|
|Conjugate||This FOXO1 antibody is un-conjugated Alternatives|
Dot Blot (DB)
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Product Details anti-FOXO1 AntibodyTarget Details FOXO1 Application Details Handling Images
|Cross-Reactivity (Details)||Other species not studied.|
|Purification||Protein G affinity chromatography|
|Immunogen||FOXO1 A antibody was raised in mouse using recombinant Human Forkhead Box O1 (Rhabdomyosarcoma) (Foxo1 )|
Target Details FOXO1Product Details anti-FOXO1 Antibody Application Details Handling Images back to top
|Alternative Name||FOXO1A (FOXO1 Antibody Abstract)|
|Background||FOXO1 belongs to the forkhead family of transcription factors that are characterized by a distinct fork head domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. In hepatic cells this transcription factor seems to increase the expression of PEPCK and glycogen-6 phosphatase (the same enzymes that are blocked via the metformin/AMPK/SHP pathway). Blocking this transcription factor offers an opportunity for novel therapies for diabetes mellitus. Synonyms: Monoclonal FOXO1A antibody, Anti-FOXO1A antibody, Forkhead box protein O1 antibody, FKH1 antibody, FKHR antibody, FOXO1 antibody.|
|Research Area||Cancer, Transcription Factors, DNA/RNA|
|Pathways||PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-FOXO1 Antibody Target Details FOXO1 Handling Images back to top
|Application Notes||Optimal conditions should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Images back to top
|Buffer||FOXO1 A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.|
ImagesProduct Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Handling back to top