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|Antigen||Forkhead Box O1 (FOXO1) Antibodies|
|Epitope||Middle Region Alternatives|
|Conjugate||This FOXO1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-FOXO1 AntibodyTarget Details FOXO1 Application Details Handling References for anti-FOXO1 antibody (ABIN453020) Images
|Specificity||This antibody detects FOXO1A at Center, D469.|
|Cross-Reactivity (Details)||Species reactivity (tested):Human|
|Purification||Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS|
|Immunogen||KLH conjugated synthetic peptide selected from the Center region of human FKHR|
Target Details FOXO1Product Details anti-FOXO1 Antibody Application Details Handling References for anti-FOXO1 antibody (ABIN453020) Images back to top
|Alternative Name||FOXO1A (FOXO1 Antibody Abstract)|
|Background||FKHR belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain.Synonyms: FKHR, FOXO1, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead in Rhabdomyosarcoma|
|Molecular Weight||69662 Da|
|Research Area||Cancer, Transcription Factors|
|Pathways||PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-FOXO1 Antibody Target Details FOXO1 Handling References for anti-FOXO1 antibody (ABIN453020) Images back to top
Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FOXO1 Antibody Target Details FOXO1 Application Details References for anti-FOXO1 antibody (ABIN453020) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.|
References for anti-FOXO1 antibody (ABIN453020)Product Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Handling Images back to top
Lau, Koty, Nalbantoglu: "Differential response of glioma cells to FOXO1-directed therapy." in: Cancer research, Vol. 69, Issue 13, pp. 5433-40, 2009
Jung, Lee, Kim, Jung, Seo, Kim, Cho, Lee, Park, Lee: "Forkhead transcription factor FoxO1 inhibits insulin- and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression." in: Biochemical and biophysical research communications, Vol. 386, Issue 4, pp. 757-61, 2009
ImagesProduct Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Handling References for anti-FOXO1 antibody (ABIN453020) back to top