anti-Human FOXO1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended FOXO1 Antibody (supplied by: Log in to see )

Antigen
Forkhead Box O1 (FOXO1) Antibodies
  • FOXO1
  • FOXO1A
  • fkh1
  • fkhr
  • foxo1a
  • xFoxO1
  • FKH1
  • FKHR
  • AI876417
  • Afxh
  • Fkhr1
  • Foxo1a
  • Fkhr
  • FoxO1A
  • FoxO1a.1
  • foxo1
  • zgc:153388
  • forkhead box O1
  • forkhead box O1 a
  • FOXO1
  • foxo1
  • Foxo1
  • foxo1a
Epitope
AA 315-325, pSer319
54
35
32
27
22
19
18
17
16
10
10
9
8
8
5
5
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
470
253
201
35
29
21
14
12
8
7
5
3
3
3
3
2
2
1
1
Host
Rabbit
320
134
21
2
Clonality
Polyclonal
Conjugate
This FOXO1 antibody is un-conjugated
11
11
9
8
8
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
2
2
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
381
207
135
134
131
83
55
12
9
9
5
4
4
4
3
3
2
1
Options
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Catalog No. ABIN684733
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN741720 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN1709956 IF (p) FITC Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1708145 IF (p) Cy7 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1706334 IF (p) Cy5.5 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1695304 IF (p) Alexa Fluor 488 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1697128 IF (p) Alexa Fluor 555 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1698939 IF (p) Alexa Fluor 647 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1704376 IF (p) Cy5 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1702565 IF (p) Cy3 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN1693485 IF (p) Alexa Fluor 350 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN2813357 IF (p) Alexa Fluor 594 Rabbit IgG AA 230-280 Log in to see Polyclonal
1 ABIN2813361 IF (p) Alexa Fluor 594 Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
1 ABIN2813356 IF (p) Alexa Fluor 594 Rabbit IgG pSer329 Log in to see Polyclonal
1 ABIN741723 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN741724 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN741725 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN741727 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN741726 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1697127 IF (p) Alexa Fluor 555 Rabbit IgG pSer329 Log in to see Polyclonal
1 ABIN1709955 IF (p) FITC Rabbit IgG pSer329 Log in to see Polyclonal

General

Antigen Forkhead Box O1 (FOXO1) Antibodies
Epitope AA 315-325, pSer319
(54), (35), (32), (27), (22), (19), (18), (17), (16), (10), (10), (9), (8), (8), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(470), (253), (201), (35), (29), (21), (14), (12), (8), (7), (5), (3), (3), (3), (3), (2), (2), (1), (1)
Host Rabbit
(320), (134), (21), (2)
Clonality
Polyclonal
Conjugate This FOXO1 antibody is un-conjugated
(11), (11), (9), (8), (8), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(381), (207), (135), (134), (131), (83), (55), (12), (9), (9), (5), (4), (4), (4), (3), (3), (2), (1)
Pubmed 1 reference available
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Product Details anti-FOXO1 Antibody

Target Details FOXO1 Application Details Handling ProductDetails: References for anti-FOXO1 antibody (ABIN684733) Images
Specificity This phosphorylation site is found at Ser316 in mouse, Ser313 in rat
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human FoxO1 around the phosphorylation site of Ser319 [TS(p-S)NA]
Isotype IgG

Target Details FOXO1

Product Details anti-FOXO1 Antibody Application Details Handling ProductDetails: References for anti-FOXO1 antibody (ABIN684733) Images back to top
Antigen
Alternative Name Foxo1 (FOXO1 Antibody Abstract)
Background

Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

Subcellular location: Cytoplasm, Nucleus

Synonyms: FKH1, FKHR, FOXO1A, Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FOXO1

Gene ID 2308
UniProt Q12778
Pathways PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events

Application Details

Product Details anti-FOXO1 Antibody Target Details FOXO1 Handling ProductDetails: References for anti-FOXO1 antibody (ABIN684733) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-FOXO1 Antibody Target Details FOXO1 Application Details ProductDetails: References for anti-FOXO1 antibody (ABIN684733) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-FOXO1 antibody (ABIN684733)

Product Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Handling Images back to top
Product cited in:

Lowther, Goods, Lucca, Lerner, Raddassi, van Dijk, Hernandez, Duan, Gunel, Coric, Krishnaswamy, Love, Hafler: "PD-1 marks dysfunctional regulatory T cells in malignant gliomas." in: JCI insight, Vol. 1, Issue 5, 2016

Images

Product Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Handling ProductDetails: References for anti-FOXO1 antibody (ABIN684733) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Forkhead Box O1 (FOXO1) (AA 315-325), (pSer319) antibody (ABIN684733) Formalin-fixed and paraffin-embedded rat kidney tissue labeled with Rabbit Anti-Phosp...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Forkhead Box O1 (FOXO1) (AA 315-325), (pSer319) antibody (ABIN684733) Formalin-fixed and paraffin embedded rat testis labeled with Rabbit Anti-FoxO1 (Ser31...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Forkhead Box O1 (FOXO1) (AA 315-325), (pSer319) antibody (ABIN684733) Formalin-fixed and paraffin-embedded rat kidney tissue labeled with Rabbit Anti-Phosp...